Levetiracetam
- Generic Name
- Levetiracetam
- Brand Names
- Elepsia, Keppra, Matever, Roweepra, Spritam, Levetiracetam Accord, Levetiracetam Teva, Levetiracetam Actavis, Levetiracetam ratiopharm, Levetiracetam Sun, Levetiracetam Actavis Group, Levetiracetam Hospira
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14N2O2
- CAS Number
- 102767-28-2
- Unique Ingredient Identifier
- 44YRR34555
- Background
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). Levetiracetam possesses a wide therapeutic index and little-to-no potential t...
- Indication
Levetiracetam is indicated as an adjunctive therapy in the treatment of partial onset seizures in epileptic patients who are one month of age and older. Additionally, it is indicated as an adjunct in the treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy who are 12 years of age and older, and in primary generalized tonic-clonic seiz...
- Associated Conditions
- Epilepsies, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Myoclonic seizures
- Associated Therapies
- -
Dosing of Levetiracetam (Keppra) in Neonates
- Conditions
- First Posted Date
- 2010-11-11
- Last Posted Date
- 2021-09-05
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 7
- Registration Number
- NCT01239212
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset Seizures
- First Posted Date
- 2010-10-28
- Last Posted Date
- 2017-08-15
- Lead Sponsor
- UCB Korea Co., Ltd.
- Target Recruit Count
- 343
- Registration Number
- NCT01229735
- Locations
- 🇰🇷
18, Seoul, Korea, Republic of
🇰🇷13, Daegu, Korea, Republic of
🇰🇷23, Kyunggi-Do, Korea, Republic of
A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures)
- Conditions
- Interventions
- First Posted Date
- 2010-10-26
- Last Posted Date
- 2019-01-15
- Lead Sponsor
- UCB Japan Co. Ltd.
- Target Recruit Count
- 361
- Registration Number
- NCT01228747
- Locations
- 🇯🇵
152, Fujisawa, Japan
🇯🇵170, Saito, Japan
🇯🇵153, Kashiwakazi, Japan
Bioequivalence Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fed Conditions
- First Posted Date
- 2010-05-28
- Last Posted Date
- 2010-06-14
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 24
- Registration Number
- NCT01132352
- Locations
- 🇺🇸
MDS Pharma Services, Neptune, New Jersey, United States
Bioavailability Study of Levetiracetam Tablets, 750 mg of Dr. Reddy's Under Fasting Conditions.
- First Posted Date
- 2010-05-27
- Last Posted Date
- 2010-06-14
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 24
- Registration Number
- NCT01131897
- Locations
- 🇺🇸
MDS Pharma Services, Neptune, New Jersey, United States
An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures
- First Posted Date
- 2010-02-05
- Last Posted Date
- 2015-03-05
- Lead Sponsor
- UCB Japan Co. Ltd.
- Target Recruit Count
- 73
- Registration Number
- NCT01063764
- Locations
- 🇯🇵
10, Koushi, Japan
🇯🇵31, Kurume, Japan
🇯🇵8, Neyagawa, Japan
Cognitive Effects of Treatment of Interictal Discharges
- First Posted Date
- 2009-06-09
- Last Posted Date
- 2018-10-03
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 31
- Registration Number
- NCT00916149
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism
- Conditions
- Interventions
- First Posted Date
- 2009-03-17
- Last Posted Date
- 2015-04-28
- Lead Sponsor
- Boston Medical Center
- Target Recruit Count
- 85
- Registration Number
- NCT00862563
- Locations
- 🇺🇸
Boston University School of Medicine, Boston, Massachusetts, United States
Levetiracetam 1000 mg Under Non-Fasting Conditions
- First Posted Date
- 2009-03-11
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- Teva Pharmaceuticals USA
- Target Recruit Count
- 22
- Registration Number
- NCT00859430
- Locations
- 🇺🇸
CEDRA Clinical Research, LLC, San Antonio, Texas, United States
Levetiracetam 1000 mg Under Fasting Conditions
- First Posted Date
- 2009-03-11
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- Teva Pharmaceuticals USA
- Target Recruit Count
- 30
- Registration Number
- NCT00859521
- Locations
- 🇺🇸
CEDRA Clinical Research, LLC, San Antonio, Texas, United States
Drug Development Updates
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