Reserpine
- Generic Name
- Reserpine
- Brand Names
- Renese-R
- Drug Type
- Small Molecule
- Chemical Formula
- C33H40N2O9
- CAS Number
- 50-55-5
- Unique Ingredient Identifier
- 8B1QWR724A
- Background
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit...
- Indication
For the treatment of hypertension
- Associated Conditions
- Hypertension
- Associated Therapies
- -
Effect of Intermittent Oro-esophageal Tube Feeding on Severe Traumatic Brain Injury Patients With Tracheostomy
- Conditions
- Interventions
- First Posted Date
- 2024-01-10
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- Zeng Changhao
- Target Recruit Count
- 104
- Registration Number
- NCT06199778
- Locations
- 🇨🇳
Zheng da yi fu yuan hospital, Zhengzhou, Henan, China
Mechanisms of Refractory Hypertension (Reserpine)
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2021-11-30
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 7
- Registration Number
- NCT03223272
- Locations
- 🇺🇸
UAB, Birmingham, Alabama, United States
A Study of Stellate Ganglion Block and / or Reserpine in Group 2 Pulmonary Hypertension
- Conditions
- Interventions
- First Posted Date
- 2016-02-18
- Last Posted Date
- 2019-05-22
- Lead Sponsor
- Mayo Clinic
- Registration Number
- NCT02684786
- Locations
- 🇺🇸
Mayo Clinic Florida, Jacksonville, Florida, United States
A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1
- Conditions
- First Posted Date
- 2005-12-21
- Last Posted Date
- 2017-01-11
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 30
- Registration Number
- NCT00267657
- Locations
- 🇺🇸
U of CA, San Francisco, San Francisco, California, United States
Reserpine for the Treatment of Cocaine Dependence - 1
- Conditions
- First Posted Date
- 2002-04-08
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 140
- Registration Number
- NCT00033033
- Locations
- 🇺🇸
Cincinnati VA Medical Center, Cincinnati, Ohio, United States
🇺🇸Dayton VA Medical Center, Dayton, Ohio, United States
🇺🇸Boston University Medical Center, Boston, Massachusetts, United States
Systolic Hypertension in the Elderly Program (SHEP)
- Conditions
Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
- Conditions
Drug Development Updates
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