Ibudilast

Generic Name
Ibudilast
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C14H18N2O
CAS Number
50847-11-5
Unique Ingredient Identifier
M0TTH61XC5
Background

Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume shrinkage in patients with relapsing-remitting (RR) and/or secondary progressive (SP) multiple sclerosis (MS). Ibudilast is currently in development in the...

Indication

For the treatment of multiple sclerosis, asthma, and cerebrovascular disease.

Associated Conditions
-
Associated Therapies
-

Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis

First Posted Date
2013-11-13
Last Posted Date
2020-07-28
Lead Sponsor
MediciNova
Target Recruit Count
255
Registration Number
NCT01982942
Locations
🇺🇸

University at Buffalo, The State University of New York, Buffalo, New York, United States

🇺🇸

Cornell Medical College, New York, New York, United States

🇺🇸

University of Virginia Charlottesville, Charlottesville, Virginia, United States

and more 25 locations

Trial of Ibudilast for Methamphetamine Dependence

First Posted Date
2013-05-23
Last Posted Date
2019-01-30
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
125
Registration Number
NCT01860807
Locations
🇺🇸

UCLA Vine Street Clinic, Los Angeles, California, United States

Ibudilast in the Treatment of Patients With Chronic Migraine.

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-07-08
Last Posted Date
2015-12-29
Lead Sponsor
Parisa Gazerani
Target Recruit Count
33
Registration Number
NCT01389193
Locations
🇦🇺

School of Medical sciences, University of Adelaide, Adelaide, Australia

Ibudilast in the Treatment of Medication Overuse Headache

First Posted Date
2011-03-18
Last Posted Date
2013-02-06
Lead Sponsor
University of Adelaide
Target Recruit Count
40
Registration Number
NCT01317992
Locations
🇦🇺

Pain and Anaesthesia Research Clinic, Royal Adelaide Hospital, Adelaide, South Australia, Australia

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