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MediciNova

🇺🇸United States
Ownership
-
Employees
-
Market Cap
$71.6M
Website
Introduction

MediciNova Inc is a biopharmaceutical company. The company acquires and develops small-molecule therapeutics for the treatment of diseases with unmet medical needs with a specific focus on the U.S. market. Its products portfolio includes therapeutics such as MN-001, MN-166, MN-221 etc. The firm's current strategy is to focus its development activities on therapeutics for neurological disorders and fibrotic diseases.

Clinical Trials

17

Active:0
Completed:14

Trial Phases

2 Phases

Phase 1:6
Phase 2:11

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (17 trials with phase data)• Click on a phase to view related trials

Phase 2
11 (64.7%)
Phase 1
6 (35.3%)

MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia

Phase 2
Recruiting
Conditions
Non-Alcoholic Fatty Liver Disease
Diabetes Mellitus, Type 2
Hypertriglyceridemia
Interventions
Drug: MN-001 placebo
First Posted Date
2022-07-19
Last Posted Date
2025-04-08
Lead Sponsor
MediciNova
Target Recruit Count
40
Registration Number
NCT05464784
Locations
🇺🇸

Pinnacle Clinical Research at South Texas Research Institute, Edinburg, Texas, United States

🇺🇸

Jubilee Clinical Research, Inc., Las Vegas, Nevada, United States

Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at Risk for ARDS

Phase 2
Completed
Conditions
Pneumonia, Viral
Interventions
Drug: Placebo
First Posted Date
2020-06-12
Last Posted Date
2024-10-30
Lead Sponsor
MediciNova
Target Recruit Count
34
Registration Number
NCT04429555
Locations
🇺🇸

Denver Health and Hospital Authority, Denver, Colorado, United States

🇺🇸

Yale University School of Medicine, New Haven, Connecticut, United States

Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS

Phase 2
Recruiting
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Drug: placebo
First Posted Date
2019-08-15
Last Posted Date
2025-05-08
Lead Sponsor
MediciNova
Target Recruit Count
230
Registration Number
NCT04057898
Locations
🇺🇸

University of California, Orange, California, United States

🇺🇸

Mayo Clinic, Jacksonville, Florida, United States

🇺🇸

Augusta University, Augusta, Georgia, United States

and more 13 locations

Relative Bioavailability of MN-166 (Ibudilast) in Extended Release Tablet vs. Intermediate-release Capsule in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
First Posted Date
2019-08-13
Last Posted Date
2020-07-15
Lead Sponsor
MediciNova
Target Recruit Count
12
Registration Number
NCT04054206
Locations
🇺🇸

Collaborative Neuroscience Network, Garden Grove, California, United States

Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma

Phase 1
Completed
Conditions
Newly Diagnosed Glioblastoma
Recurrent Glioblastoma
GBM
Glioblastoma
Interventions
First Posted Date
2018-12-20
Last Posted Date
2025-05-21
Lead Sponsor
MediciNova
Target Recruit Count
64
Registration Number
NCT03782415
Locations
🇺🇸

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

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News

First Patient Enrolled in NIH-Funded Expanded Access Program for MN-166 in Advanced ALS

MediciNova has enrolled the first patient in an NIH-funded Expanded Access Program trial evaluating MN-166 (ibudilast) in approximately 200 ALS patients who are ineligible for the ongoing Phase 2/3 COMBAT-ALS trial.

MediciNova's Ibudilast Shows Promise in ALS Trial: Interim Analysis Reveals Strong Correlations

MediciNova's COMBAT-ALS Phase 2/3 trial of MN-166 (ibudilast) in ALS shows positive correlations between 6-month and 12-month data for key metrics.

Ibudilast Expanded Access Program for ALS Patients Managed by Widetrial

Widetrial will manage the physician network for an expanded access program (EAP) providing ibudilast (MN-166) to ALS patients ineligible for clinical trials.

MediciNova's Ibudilast (MN-166) Shows Promise in ALS Treatment: Phase 2/3 Trial Update

MediciNova presented an update on its Phase 2/3 COMBAT-ALS trial of MN-166 (ibudilast) for amyotrophic lateral sclerosis (ALS) at the 2024 Annual NEALS Meeting.

MediciNova's Ibudilast (MN-166) Shows Promise in COMBAT-ALS Trial: Interim Analysis to be Presented at International Symposium

MediciNova's MN-166 (ibudilast) abstract, detailing the COMBAT-ALS trial for ALS treatment, has been accepted for a poster presentation.

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