MedPath

Reboxetine

Generic Name
Reboxetine
Drug Type
Small Molecule
Chemical Formula
C19H23NO3
CAS Number
71620-89-8
Unique Ingredient Identifier
947S0YZ36I
Background

Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

Indication

For the treatment of clinical depression.

Associated Conditions
Major Depressive Disorder (MDD)
Associated Therapies
Maintenances

Cognitive Flexibility in Major Depression in the Course of Pharmacological and Psychotherapeutic Treatment

Not Applicable
Completed
Conditions
Cognitive Performance in Major Depression
Interventions
Behavioral: interpersonal psychotherapy
First Posted Date
2009-10-14
Last Posted Date
2009-10-14
Lead Sponsor
Zentrum für Integrative Psychiatrie
Target Recruit Count
45
Registration Number
NCT00993876
Locations
🇩🇪

Zentrum für Integrative Psychiatrie, Kiel, Germany

Enhancement of Motor Function with Reboxetine and Transcranial Direct Current Stimulation

Phase 4
Completed
Conditions
Cerebral Stroke
Interventions
Drug: Placebo
Device: tDCS sham
Device: tDCS verum
First Posted Date
2009-03-02
Last Posted Date
2024-12-10
Lead Sponsor
Universitätsklinikum Hamburg-Eppendorf
Target Recruit Count
12
Registration Number
NCT00853866
Locations
🇩🇪

University Hospital Hamburg-Eppendorf, Department of Neurology, Hamburg, HH, Germany

Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study

Phase 4
Conditions
Depression
First Posted Date
2007-01-25
Last Posted Date
2007-01-25
Lead Sponsor
Geha Mental Health Center
Target Recruit Count
60
Registration Number
NCT00426946
Locations
🇮🇱

Tel Aviv Community Mental Helath Center, Tel Aviv, Israel

Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.

Not Applicable
Completed
Conditions
Major Depressive Disorder
First Posted Date
2007-01-12
Last Posted Date
2013-03-22
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
35
Registration Number
NCT00421369
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem, Israel

Reboxetine Adjuvant Therapy for the Treatment of Schizophrenia

Phase 1
Conditions
Schizophrenia
First Posted Date
2006-12-08
Last Posted Date
2006-12-08
Lead Sponsor
Abarbanel Mental Health Center
Target Recruit Count
30
Registration Number
NCT00409201
Locations
🇮🇱

Abarbanel Medical Mental Health Center, Bat Yam, Israel

Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder

Phase 4
Conditions
Major Depression
Pain
Abdominal Pain
Interventions
First Posted Date
2005-09-21
Last Posted Date
2010-05-27
Lead Sponsor
Hospital Universitari Vall d'Hebron Research Institute
Target Recruit Count
42
Registration Number
NCT00209807
Locations
🇪🇸

Hospital Universitari vall d'Hebron, Barcelona, Catalonia, Spain

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