MedPath

Pardoprunox

Generic Name
Pardoprunox
Drug Type
Small Molecule
Chemical Formula
C12H15N3O2
CAS Number
269718-84-5
Unique Ingredient Identifier
5R72CHP32S
Background

Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.

A Pilot Study to Assess Efficacy and Safety of Pardoprunox as Adjunct Therapy to L-dopa in the Treatment of Patients With Parkinson's Disease Experiencing Motor Fluctuations and Dyskinesia.

Phase 2
Terminated
Conditions
Advanced Stage Parkinson's Disease
Interventions
First Posted Date
2009-05-18
Last Posted Date
2011-08-26
Lead Sponsor
Abbott Products
Target Recruit Count
37
Registration Number
NCT00903838
Locations
๐Ÿ‡ฎ๐Ÿ‡น

Site Reference ID/Investigator# 45435, Cassino, Italy

๐Ÿ‡ฎ๐Ÿ‡น

Site Reference ID/Investigator# 45436, Chieti Scalo, Italy

๐Ÿ‡ฉ๐Ÿ‡ช

Site Reference ID/Investigator# 45422, Tuebingen, Germany

and more 6 locations

An Open Label SLV308 Safety Extension to Study S308.3.002 in Patients With Parkinson's Disease Experiencing Motor Fluctuations.

Phase 3
Completed
Conditions
Advanced Stage Parkinson's Disease
Interventions
First Posted Date
2006-12-04
Last Posted Date
2010-09-13
Lead Sponsor
Solvay Pharmaceuticals
Target Recruit Count
140
Registration Number
NCT00407095
Locations
๐Ÿ‡บ๐Ÿ‡ธ

S308.3.007 Site # 221, Chicago, Illinois, United States

๐Ÿ‡ง๐Ÿ‡ฌ

S308.3.007 Site # 120, Sofia, Bulgaria

๐Ÿ‡จ๐Ÿ‡ฑ

S308.3.007 Site # 141, Santiago de Chile, Chile

and more 84 locations

An Open Label SLV308 Safety Extension to Study S308.3.003 in Early PD Patients

Phase 3
Completed
Conditions
Early Stage Parkinson's Disease
Interventions
First Posted Date
2006-06-09
Last Posted Date
2009-02-06
Lead Sponsor
Solvay Pharmaceuticals
Target Recruit Count
202
Registration Number
NCT00335374
Locations
๐Ÿ‡จ๐Ÿ‡ณ

389, Kaohsiung Hsien, Taiwan

๐Ÿ‡จ๐Ÿ‡ณ

387, Kaohsiung, Taiwan

๐Ÿ‡ต๐Ÿ‡ฑ

368, Leszno, Poland

and more 72 locations

An Open Label SLV308 Safety Extension to Study S308.3.001 in Early PD Patients

Phase 3
Completed
Conditions
Early Stage Parkinson's Disease
Interventions
First Posted Date
2006-06-02
Last Posted Date
2009-01-26
Lead Sponsor
Solvay Pharmaceuticals
Target Recruit Count
224
Registration Number
NCT00332917
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Site 281, Pittsburgh, Pennsylvania, United States

๐Ÿ‡จ๐Ÿ‡ฆ

Site 269, Saskatoon, Canada

๐Ÿ‡ฆ๐Ÿ‡ท

Site 208, Capital Federal, CBA, Argentina

and more 127 locations

SLV308 for Treatment of Patients With Early Parkinson's Disease

Phase 3
Completed
Conditions
Early Stage Parkinson's Disease
Interventions
Drug: Placebo
First Posted Date
2005-12-23
Last Posted Date
2008-08-29
Lead Sponsor
Solvay Pharmaceuticals
Target Recruit Count
468
Registration Number
NCT00269516
Locations
๐Ÿ‡ง๐Ÿ‡ช

Site 100, Brussels, Belgium

๐Ÿ‡ง๐Ÿ‡ฌ

Site 107, Plovdiv, Bulgaria

๐Ÿ‡ง๐Ÿ‡ฌ

Site 104, Sofia, Bulgaria

and more 125 locations

Ascending Dose Tolerability/Safety of SLV308 for the Treatment of Parkinson's Disease

Phase 3
Completed
Conditions
Parkinson's Disease
First Posted Date
2005-08-24
Last Posted Date
2009-01-30
Lead Sponsor
Solvay Pharmaceuticals
Registration Number
NCT00134251
Locations
๐Ÿ‡ท๐Ÿ‡ธ

Site 34, Belgrade, Serbia

๐Ÿ‡ง๐Ÿ‡ฌ

Site 14, Sofia, Bulgaria

๐Ÿ‡ท๐Ÿ‡ธ

Site 33, Nis, Serbia

and more 7 locations
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