Ridaforolimus
- Generic Name
- Ridaforolimus
- Drug Type
- Small Molecule
- Chemical Formula
- C53H84NO14P
- CAS Number
- 572924-54-0
- Unique Ingredient Identifier
- 48Z35KB15K
- Indication
Investigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases.
Ridaforolimus (AP23573/MK-8669) in Participants With Taxane-Resistant Androgen-Independent Prostate Cancer (AIPC)(MK-8669-017)
- First Posted Date
- 2005-05-05
- Last Posted Date
- 2015-11-20
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 39
- Registration Number
- NCT00110188
- Locations
- 🇺🇸
Louis Warchaw Prostate Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸University of Wisconsin, Madison, WI, Madison, Wisconsin, United States
🇺🇸Beth Israel Deaconess Medical Center/MGH/DFCI, Boston, Massachusetts, United States
Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)
- Conditions
- LeiomyosarcomaMetastasesLiposarcomaOsteosarcomaSarcoma, Soft Tissue
- Interventions
- First Posted Date
- 2004-10-04
- Last Posted Date
- 2015-02-13
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 216
- Registration Number
- NCT00093080
Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)
- Conditions
- Malignant GliomaGlioblastomaGliosarcoma
- First Posted Date
- 2004-07-13
- Last Posted Date
- 2015-08-19
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 11
- Registration Number
- NCT00087451
- Locations
- 🇺🇸
The Brain Tumor Center at Duke, Duke University Medical Center, Durham, North Carolina, United States
🇺🇸Brain Tumor Institute, The Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸M.D. Anderson Cancer Center, Houston, Texas, United States
Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)
- Conditions
- Myelodysplastic SyndromesHematologic MalignanciesLeukemiaMyeloid MetaplasiaLymphoma
- Interventions
- First Posted Date
- 2004-06-28
- Last Posted Date
- 2015-08-19
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 57
- Registration Number
- NCT00086125
- Locations
- 🇺🇸
University of Chicago Hospitals, Section of Hematology/Oncology, Chicago, Illinois, United States
🇺🇸The Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
🇺🇸MD Anderson Cancer Center, Houston, Texas, United States
Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)
- First Posted Date
- 2003-05-12
- Last Posted Date
- 2015-08-27
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 46
- Registration Number
- NCT00060632
Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)
- First Posted Date
- 2003-05-12
- Last Posted Date
- 2015-08-27
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 33
- Registration Number
- NCT00060645
- Locations
- 🇺🇸
Cancer Therapy and Research Center, University of Texas Health Center at San Antonio, San Antonio, Texas, United States
Drug Development Updates
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