Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of gastrointestinal infections including Cryptosporidium parvum or Giardia lamblia in healthy subjects. It is generally well tolerated. Nitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment of illnesses caused by other protozoa or helminths . Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses .
用于治疗隐孢子虫、贾第鞭毛虫、阿米巴原虫引起的原虫性腹泻。
Benha University Hospital, Benha, Egypt
University Hospital, Alexandria, Egypt
Benha University Hospital, Benha, Egypt
University Hospital, Alexandria, Egypt
Baylor College of Medicine, Houston, Texas, United States
Michael E. Debakey VA Medical Center, Houston, Texas, United States
Gastrointestinal Associates, LLC, Kingsport, Tennessee, United States
Nashville Medical Research, Nashville, Tennessee, United States
Romark Laboratories, L.C., Tampa, Florida, United States
Siriraj Hospital Mahidol University CRS, Bangkok, Thailand
Stellenbosch Univ. CRS, Cape Town, South Africa
Cook County Hosp. CORE Ctr., Chicago, Illinois, United States
Julie Ryner, Tampa, Florida, United States
New York Hosp / Cornell Med Ctr, New York, New York, United States
Romark Laboratories LC, Tampa, Florida, United States
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