Erythropoietin

Generic Name
Erythropoietin
Brand Names
Procrit, Eprex, Epprex, Epoetin Alfa Hexal, Silapo, Biopoin, Abseamed, Eporatio, NeoRecormon, Epogen, Retacrit
Drug Type
Biotech
Chemical Formula
-
CAS Number
11096-26-7
Unique Ingredient Identifier
64FS3BFH5W
Background

Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow . Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alf...

Indication

用于肾功能不全合并的贫血,艾滋病本身或因治疗引起的贫血,恶性肿瘤伴发的贫血及风湿性贫血等。另外,为择期手术储存自体血而反复采血的患者,同时应用本品可预防发生贫血。

Associated Conditions
Anemia, Blood Loss During Surgery, Anemia caused by Zidovudine
Associated Therapies
-

Impact of Erythropoietin Administration During Definitive Cervix Cancer Radiotherapy on Treatment Outcome

Phase 3
Conditions
Interventions
First Posted Date
2006-07-06
Last Posted Date
2007-11-02
Lead Sponsor
Medical University of Vienna
Target Recruit Count
300
Registration Number
NCT00348738
Locations
🇦🇹

Department of Radiotherapy-University Hospital of Salzburg, Salzburg, Austria

🇦🇹

Department of Radiotherapy-University Hospital of Innsbruck, Innsbruck, Austria

🇦🇹

Department of Radiotherapy and Radiobiology-Medical University of Vienna, Vienna, Austria

and more 1 locations

REPEAT Study - Resistance to ErythroPoietin Effectiveness Algorithm Trial

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2006-04-27
Last Posted Date
2009-02-12
Lead Sponsor
Queen's University
Target Recruit Count
6
Registration Number
NCT00319150
Locations
🇨🇦

Foothills Hospital, Calgary, Alberta, Canada

🇨🇦

St. Paul's Hospital, Vancouver, British Columbia, Canada

🇨🇦

Humber River Regional Hosptial, Toronto, Ontario, Canada

and more 4 locations

Preliminary Administration of EPO and Markers of Cardiac Ischemia Induced by CPB

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-01-09
Last Posted Date
2009-12-07
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
50
Registration Number
NCT00273767
Locations
🇫🇷

Cardiac Surgery Department - CHU de Grenoble, Grenoble, France

Assess Functional Outcomes in Anemic, Critically Ill, Trauma Patients When Taking Epoetin Alfa

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2005-09-21
Last Posted Date
2014-04-21
Lead Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Target Recruit Count
192
Registration Number
NCT00210626

PROTECT: Prospective Trial on Erythropoietin in Clinical Transplantation

First Posted Date
2005-09-12
Last Posted Date
2010-08-02
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
92
Registration Number
NCT00157300
Locations
🇳🇱

Leiden University Medical Center, Leiden, Netherlands

🇳🇱

Other transplantation centers, To Be Determined, Netherlands

Erythropoietin in Acute Myocardial Infarction

First Posted Date
2005-09-08
Last Posted Date
2005-09-08
Lead Sponsor
Hammersmith Hospitals NHS Trust
Target Recruit Count
124
Registration Number
NCT00149058
Locations
🇬🇧

Hammersmith Hospital NHS Trust, London, United Kingdom

🇬🇧

King's College London, London, United Kingdom

Treatment for Patients With Non-Myeloid Malignancies Receiving Chemotherapy

First Posted Date
2005-05-18
Last Posted Date
2008-02-28
Lead Sponsor
Amgen
Target Recruit Count
718
Registration Number
NCT00111137

Anemia in Patients With a Non-Myeloid Malignancy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2002-05-29
Last Posted Date
2008-09-15
Lead Sponsor
Amgen
Target Recruit Count
707
Registration Number
NCT00038064
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