Aspirin

Generic Name: Aspirin

Brand Names: Aggrenox, Alka-seltzer, Alka-seltzer Fruit Chews, Anacin, Arthriten Inflammatory Pain, Ascomp, Aspi-cor, Aspir-low, Bayer Aspirin, Bayer Womens, Bc Arthritis, Bc Original Formula, Bufferin, Duoplavin, Durlaza, Ecotrin, Ecpirin, Endodan Reformulated May 2009, Equagesic, Exaprin, Excedrin, Excedrin PM Triple Action, Fasprin, Fiorinal, Goody's Body Pain, Goody's Extra Strength, Goody's PM, Miniprin, Norgesic, Norgesic Forte, Orphengesic, Pamprin Max Formula, Robaxisal, ST. Joseph Aspirin, Stanback Headache Powder Reformulated Jan 2011, Trianal, Trianal C, Vanquish, Vazalore, Yosprala

Drug Type: Small Molecule

Chemical Formula: C_₉H_₈O_₄

CAS Number: 50-78-2

Unique Ingredient Identifier: R16CO5Y76E

Background: Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) .
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Indication: Pain, fever, and inflammation
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Associated Conditions: Acute Coronary Syndrome (ACS), Anxiety, Atherothrombotic cerebral infarction, Cardiovascular Disease (CVD), Cardiovascular Events, Cardiovascular Mortality, Colorectal Adenomas, Colorectal Cancer, Common Cold, Coronary artery reocclusion, Death, Dyspeptic signs and symptoms, Fever, Flu caused by Influenza, Headache, Heterozygous Familial Hypercholesterolemia (HeFH), Inflammation, Juvenile Idiopathic Arthritis (JIA), Major Adverse Cardiovascular and Cerebrovascular Events (MACCE), Menstrual Pain, Migraine, Morbidity, Mucocutaneous Lymph Node Syndrome, Muscle Contraction, Myalgia, Myocardial Infarction, Myocardial Infarction (MI), first occurrence, Neuropathic Pain, Pain, Pain caused by Common Cold, Pain caused by Rheumatism, Pericarditis, Polycythemia Vera (PV), Pre-Eclampsia, Rheumatism, Rheumatoid Arthritis, Rhino Sinusitis, Severe Pain, Spondyloarthropathies, Stroke, Systemic Lupus Erythematosus, Tension Headache, Thromboembolism, Thrombosis, Toothache, Transient Ischemic Attack, Vascular Death, Venous Thromboembolism, Acute Inflammation, Articular inflammation, Atherothrombotic events, Death caused by Myocardial Infarction, Fever or influenza-like illness, Moderate Pain, Recurrent Ischemic Stroke

Associated Therapies: Anti-platelet Therapy, Hemodialysis Treatment, Secondary Prevention

Clinical Trials

Aspirin Non-responsiveness and Clopidogrel Endpoint Trial.

Phase 4

Completed

Conditions: Coronary Heart Disease
Angina Pectoris
Atherosclerosis

Interventions: Drug: aspirin
Drug: clopidogrel

First Posted Date: 2005-09-22

Last Posted Date: 2011-03-23

Lead Sponsor: Ullevaal University Hospital

Target Recruit Count: 1001

Registration Number: NCT00222261

Locations: 🇳🇴
Ullevaal University Hospital, Oslo, Norway

The Effects of Physical Training, ASA (Aspirin), and Clopidogrel on the Walking Capacity of Patients With Stage II Peripheral Arterial Disease (PAD)

Phase 4

Completed

Conditions: Peripheral Arterial Disease

Interventions: Drug: Aspirin
Drug: Clopidogrel

First Posted Date: 2005-09-19

Last Posted Date: 2008-10-06

Lead Sponsor: Arteriogenesis Competence Network

Target Recruit Count: 250

Registration Number: NCT00189618

Locations: 🇨🇭
University Hospital Basel Dpt. Angiology, Basel, Switzerland
🇨🇭
Ospedale San Giovanni, Bellinzona, Switzerland
🇨🇭
Kantonsspital Bruderholz, Bruderholz, Switzerland

and more 13 locations

Aspirin Prophylaxis in Sickle Cell Disease

Phase 1

Completed

Conditions: Sickle Cell Disease

Interventions: Drug: aspirin

First Posted Date: 2005-09-15

Last Posted Date: 2017-11-06

Lead Sponsor: University of Rochester

Target Recruit Count: 11

Registration Number: NCT00178464

Primary Thrombocythaemia 1 Trial

Not Applicable

Completed

Conditions: Thrombocythemia
Myeloproliferative Disorder

Interventions: Drug: Hydroxyurea
Drug: Aspirin

First Posted Date: 2005-09-15

Last Posted Date: 2017-01-18

Lead Sponsor: University of Cambridge

Target Recruit Count: 1398

Registration Number: NCT00175838

Locations: 🇬🇧
Addenbrooke's Hospital, Cambridge, Cambs, United Kingdom

PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes

Phase 4

Completed

Conditions: Stroke

Interventions: Drug: Aggrenox
Drug: Clopidogrel placebo
Drug: Aggrenox placebo
Drug: Micardis
Drug: Micardis placebo
Drug: Clopidogrel

First Posted Date: 2005-09-12

Last Posted Date: 2014-05-13

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 20332

Registration Number: NCT00153062

Locations: 🇺🇸
9.159.1197 Boehringer Ingelheim Investigational Site, Dallas, Texas, United States
🇺🇸
9.159.1024 Boehringer Ingelheim Investigational Site, Baltimore, Maryland, United States
🇺🇸
9.159.1005 Boehringer Ingelheim Investigational Site, Fort Smith, Arkansas, United States

and more 664 locations