Overview
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Background
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Indication
Antithrombin III human is a human antithrombin (AT) indicated in patients with hereditary antithrombin deficiency for the treatment and prevention of thromboembolism and prevention of peri-operative and peri-partum thromboembolism
Associated Conditions
- Hereditary antithrombin III deficiency
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2021/06/08 | Phase 3 | Recruiting | |||
2021/06/03 | N/A | Completed | |||
2021/05/24 | Phase 2 | Terminated | Enrique Ginzburg | ||
2020/12/03 | N/A | Completed | |||
2019/08/13 | Phase 1 | Withdrawn | |||
2015/12/16 | Phase 1 | Completed | |||
2014/10/30 | Phase 4 | Withdrawn | Vastra Gotaland Region | ||
2012/10/03 | Phase 1 | Terminated | |||
2012/02/10 | Phase 3 | Completed | |||
2010/09/14 | Phase 4 | UNKNOWN | University of Bari |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| Anbinex Powder For Injection 1000 I.U. | SIN13683P | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 1000 I.U. per 20ml | 8/6/2009 | |
| Anbinex Powder For Injection 500 I.U. | SIN13682P | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 500 I.U. per 10ml | 8/6/2009 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| THROMBOTROL-VF antithrombin III 1000IU powder for injection vial and diluent vial | 66736 | Medicine | A | 4/8/1999 | |
| CSL NEW ZEALAND THROMBOTROL-VF Antithrombin III concentrate (human) powder for injection vial | 66708 | Medicine | A | 10/28/1998 |