Antithrombin III human
- Generic Name
- Antithrombin III human
- Brand Names
- Thrombate III
- Drug Type
- Biotech
- CAS Number
- 9000-94-6
- Unique Ingredient Identifier
- T0LTO7L82X
- Background
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
- Indication
Antithrombin III human is a human antithrombin (AT) indicated in patients with hereditary antithrombin deficiency for the treatment and prevention of thromboembolism and prevention of peri-operative and peri-partum thromboembolism
- Associated Conditions
- Hereditary antithrombin III deficiency
Use of Antithrombin in Cardiac Surgery With Cardiopulmonary Bypass
Phase 2
Completed
- Conditions
- Acquired Antithrombin III DeficiencyCoronary Artery Bypass
- Interventions
- First Posted Date
- 2009-01-15
- Last Posted Date
- 2016-09-20
- Lead Sponsor
- Instituto Grifols, S.A.
- Target Recruit Count
- 200
- Registration Number
- NCT00823082
- Locations
- 🇮🇹
IRCCS Policlinico San Donato, Milano, Lombardy, Italy
Safety, Pharmacokinetics and Efficacy of an ATIII Concentrate
Phase 2
Active, not recruiting
- Conditions
- Antithrombin III Deficiency
- Interventions
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2023-08-25
- Lead Sponsor
- Grifols Biologicals, LLC
- Target Recruit Count
- 30
- Registration Number
- NCT00319228
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