Escitalopram

Generic Name
Escitalopram
Brand Names
Cipralex, Lexapro
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
128196-01-0
Unique Ingredient Identifier
4O4S742ANY
Background

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...

Indication

Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...

Associated Conditions
Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
Associated Therapies
-

Depression, Epinephrine, and Platelet Function

First Posted Date
2005-09-14
Last Posted Date
2015-07-23
Lead Sponsor
Emory University
Target Recruit Count
40
Registration Number
NCT00166114
Locations
🇺🇸

Emory University School of Medicine, Atlanta, Georgia, United States

Escitalopram as a Treatment for Pain in Polyneuropathy

Phase 4
Completed
Conditions
First Posted Date
2005-09-13
Last Posted Date
2007-04-24
Lead Sponsor
Odense University Hospital
Target Recruit Count
50
Registration Number
NCT00162968
Locations
🇩🇰

Danish Pain Research Center, Aarhus University Hospital, Noerrebrogade 44, Aarhus, Denmark

🇩🇰

Dept. of Neurology, Odense University Hospital, Sdr. Boulevard 29, Odense, Denmark

The Efficacy of Escitalopram for Negative Symptoms in Schizophrenia

Phase 3
Completed
Conditions
First Posted Date
2005-09-08
Last Posted Date
2007-05-03
Lead Sponsor
BeerYaakov Mental Health Center
Target Recruit Count
40
Registration Number
NCT00148447
Locations
🇮🇱

Iulian Iancu, Beer Yaakov, Israel

Specific Effects of Escitalopram on Neuroendocrine Response

Completed
Conditions
First Posted Date
2005-09-08
Last Posted Date
2009-02-05
Lead Sponsor
Queen's University
Target Recruit Count
8
Registration Number
NCT00150527
Locations
🇨🇦

Providence Centre, Mental Health Services, Kingston, Ontario, Canada

Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome

First Posted Date
2005-09-08
Last Posted Date
2014-05-20
Lead Sponsor
Stanford University
Target Recruit Count
30
Registration Number
NCT00149825
Locations
🇺🇸

Stanford University, Palo Alto, California, United States

Effectiveness of Escitalopram in the Treatment of Body Dysmorphic Disorder

First Posted Date
2005-09-08
Last Posted Date
2017-12-05
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
100
Registration Number
NCT00149799
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Rhode Island Hospital, Providence, Rhode Island, United States

Prevention of Post Traumatic Stress Disorder by Early Treatment

First Posted Date
2005-09-07
Last Posted Date
2016-02-19
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
298
Registration Number
NCT00146900
Locations
🇮🇱

Hadassah Medical Organization Jerusalem Israel, Jerusalem, Israel

DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome

Phase 4
Conditions
First Posted Date
2005-09-01
Last Posted Date
2008-12-31
Lead Sponsor
Bispebjerg Hospital
Target Recruit Count
240
Registration Number
NCT00140257
Locations
🇩🇰

Bispebjerg University Hospital, Copenhagen, Denmark

Escitalopram for the Prevention of PEGASYS-associated Depression in Hepatitis C Virus-infected Patients

First Posted Date
2005-08-29
Last Posted Date
2013-03-21
Lead Sponsor
Charite University, Berlin, Germany
Target Recruit Count
208
Registration Number
NCT00136318
Locations
🇩🇪

Department of Gastroenterolgy and Rheumatology, Sektion Hepatology, Leipzig, Germany

Study of BMS-562086 in the Treatment of Outpatients With Major Depressive Disorder

First Posted Date
2005-08-26
Last Posted Date
2010-03-02
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
271
Registration Number
NCT00135421
Locations
🇺🇸

Emory University, Atlanta, Georgia, United States

🇺🇸

Albuquerque Neuroscience, Inc., Albuquerque, New Mexico, United States

🇺🇸

University Of North Carolina At Chapel Hill, Chapel Hill, North Carolina, United States

and more 37 locations
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