Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Research Study for Major Depressive Disorder: Investigation of Glutamate Medications
- Conditions
- Interventions
- First Posted Date
- 2007-01-05
- Last Posted Date
- 2019-07-31
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 26
- Registration Number
- NCT00419003
- Locations
- 🇺🇸
Mount Sinai School of Medicine, New York, New York, United States
Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient
- Conditions
- First Posted Date
- 2006-05-24
- Last Posted Date
- 2008-10-08
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 56
- Registration Number
- NCT00329394
- Locations
- 🇫🇷
Clermont-Ferrand University Hospital, Clermont-Ferrand, France
Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia
- Conditions
- First Posted Date
- 2006-03-09
- Last Posted Date
- 2006-11-14
- Lead Sponsor
- Vilnius University
- Target Recruit Count
- 60
- Registration Number
- NCT00300794
- Locations
- 🇱🇹
Vilnius University Emergency Hospital, Vilnius, Lithuania
Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease
- First Posted Date
- 2005-11-11
- Last Posted Date
- 2009-03-13
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 3
- Registration Number
- NCT00252122
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Administration of Ketamine to Prevent the Post-operative Pain
- Conditions
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2013-07-26
- Lead Sponsor
- Institut Bergonié
- Target Recruit Count
- 230
- Registration Number
- NCT00210210
- Locations
- 🇫🇷
Institut Bergonié - Centre Régional de Luttre Contre le Cancer de Bordeaux et du Sud Ouest, Bordeaux, France
Ketamine and Postoperative Analgesia in Children
- Conditions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2007-10-23
- Lead Sponsor
- Nantes University Hospital
- Target Recruit Count
- 74
- Registration Number
- NCT00200564
- Locations
- 🇫🇷
Nantes University Hospital, Nantes, France
Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids
- Conditions
- Interventions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2016-01-14
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 40
- Registration Number
- NCT00205712
- Locations
- 🇺🇸
Washington University School of Medicine, Psychiatry Dept., St. Louis, Missouri, United States
The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients
- Conditions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2016-01-15
- Lead Sponsor
- Bayside Health
- Target Recruit Count
- 40
- Registration Number
- NCT00163969
- Locations
- 🇦🇺
The Alfred Commercial Rd Prahran, Melbourne, Victoria, Australia
Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation
- Conditions
- First Posted Date
- 2005-08-29
- Last Posted Date
- 2007-06-14
- Lead Sponsor
- Queen's University
- Target Recruit Count
- 124
- Registration Number
- NCT00137085
- Locations
- 🇨🇦
Queen's University, Kingston, Ontario, Canada
Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
- Conditions
- First Posted Date
- 2005-08-12
- Last Posted Date
- 2007-03-12
- Lead Sponsor
- Hospices Civils de Lyon
- Target Recruit Count
- 40
- Registration Number
- NCT00129597
- Locations
- 🇫🇷
Centre Hospitalier Lyon Sud, Pierre bénite, France
Drug Development Updates
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