Ketamine

Generic Name
Ketamine
Brand Names
Ketalar
Drug Type
Small Molecule
Chemical Formula
C13H16ClNO
CAS Number
6740-88-1
Unique Ingredient Identifier
690G0D6V8H
Background

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...

Indication

Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...

Associated Conditions
-
Associated Therapies
General Anesthesia, Induction and Maintenance of General Anesthesia

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-02-21
Last Posted Date
2024-11-11
Lead Sponsor
Yale University
Target Recruit Count
162
Registration Number
NCT05737693
Locations
🇮🇱

Tel Aviv University, Tel Aviv, Israel

🇺🇸

Yale University School of Medicine, New Haven, Connecticut, United States

A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric Surgeries

First Posted Date
2023-02-09
Last Posted Date
2023-02-09
Lead Sponsor
Tanta University
Target Recruit Count
60
Registration Number
NCT05719506
Locations
🇪🇬

Tanta University Hospitals, Tanta, Egypt

🇪🇬

Tanta University, Tanta, Egypt

Prevention of Shivering After Spinal Anesthesia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2023-02-08
Last Posted Date
2023-02-08
Lead Sponsor
Pakistan Air Force (PAF) Hospital Islamabad
Target Recruit Count
116
Registration Number
NCT05718011
Locations
🇵🇰

PAF Hospital Islamabad, Islamabad, Federal, Pakistan

Scheduled Intranasal Ketamine

Early Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2023-01-05
Last Posted Date
2023-04-05
Lead Sponsor
Sanford Health
Registration Number
NCT05671913

Ketamine for the Treatment for Alcohol Use Disorder in the ED

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2022-12-22
Last Posted Date
2024-06-10
Lead Sponsor
Brigham and Women's Hospital
Registration Number
NCT05661669
Locations
🇺🇸

Brigham and Women's Faulkner Hospital, Boston, Massachusetts, United States

Neuroprotective Effects of ACTH4-10PRO8-GLY9-PRO10

First Posted Date
2022-12-13
Last Posted Date
2022-12-13
Lead Sponsor
Universitas Sumatera Utara
Target Recruit Count
42
Registration Number
NCT05648526
Locations
🇮🇩

Faculty of Medicine Universitas Sumatera Utara, Medan, Sumatera Utara, Indonesia

Predictors of Intravenous Ketamine Response in TRD

First Posted Date
2022-11-23
Last Posted Date
2024-02-09
Lead Sponsor
Abraham Nunes
Target Recruit Count
40
Registration Number
NCT05625555
Locations
🇨🇦

Mood Disorders Program, Halifax, Nova Scotia, Canada

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

First Posted Date
2022-10-28
Last Posted Date
2024-04-18
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
100
Registration Number
NCT05597878
Locations
🇺🇸

Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

Analgesic Effect of Ketamine Vs Ketamine Magnesium Infusion and Their Effect on Postoperative Morphine Consumption

Phase 1
Completed
Conditions
Interventions
First Posted Date
2022-10-27
Last Posted Date
2022-10-27
Lead Sponsor
Egymedicalpedia
Target Recruit Count
100
Registration Number
NCT05596669
Locations
🇪🇬

October 6 University Hospital, Giza, Egypt

Ketamine and Stress in OCD

First Posted Date
2022-10-13
Last Posted Date
2024-04-26
Lead Sponsor
Medical University of Vienna
Target Recruit Count
30
Registration Number
NCT05577585
Locations
🇦🇹

Medical University of Vienna, Department of Psychiatry and Psychotherapy, Vienna, Austria

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