Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
Tel Aviv University, Tel Aviv, Israel
Yale University School of Medicine, New Haven, Connecticut, United States
Tanta University Hospitals, Tanta, Egypt
Tanta University, Tanta, Egypt
PAF Hospital Islamabad, Islamabad, Federal, Pakistan
Brigham and Women's Faulkner Hospital, Boston, Massachusetts, United States
Faculty of Medicine Universitas Sumatera Utara, Medan, Sumatera Utara, Indonesia
Mood Disorders Program, Halifax, Nova Scotia, Canada
Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, United States
October 6 University Hospital, Giza, Egypt
Medical University of Vienna, Department of Psychiatry and Psychotherapy, Vienna, Austria
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