Estradiol
- Generic Name
- Estradiol
- Brand Names
- Activella 1/0.5 28 Day, Activelle, Amabelz 0.5/0.1 28 Day, Angeliq 0.25/0.5 28 Day, Bijuva, Climara, Climara Pro, Combipatch, Divigel, Dotti, Elestrin, Estalis, Estrace, Estradot, Estring, Estrogel, Etyqa 0.5/0.1 28 Day, Evamist, Imvexxy 4 Mcg Starter Pack, Lopreeza 1/0.5 28 Day, Lyllana, Menostar, Mimvey, Minivelle, Myfembree, Oesclim, Oriahnn 28 Day Kit, Prefest 30 Day, Vagifem, Vivelle, Yuvafem
- Drug Type
- Small Molecule
- Chemical Formula
- C18H24O2
- CAS Number
- 50-28-2
- Unique Ingredient Identifier
- 4TI98Z838E
- Background
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays,...
- Indication
Estradiol is indicated in various preparations for the treatment of moderate to severe vasomotor symptoms and vulvar and vaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure, and for the prevention of postmenopausal osteoporosis. It is also used for the treatment of breast cancer (...
- Associated Conditions
- Atrophic Vaginitis, Breast Cancer, Breast engorgement caused by Postpartum state, Heavy Menstrual Bleeding, Hypogonadism female, Kraurosis Vulvae, Metastatic Breast Cancer, Osteoporosis, Postmenopausal Osteoporosis, Premature Ovarian Failure (POF), Prostate Cancer, Severe Pain, Urogenital atrophy, Vasomotor Symptoms Associated With Menopause, Vulvo Vaginal Atrophy, Advanced androgen dependent Prostate cancer, Female castration, Hypoestrogenism
- Associated Therapies
- Contraception, Hormone Replacement Therapy, Palliative Treatment
Effects of Hormone Replacement Therapy on Inflammation and Stiffening of Artery Walls
- Conditions
- First Posted Date
- 2000-04-12
- Last Posted Date
- 2008-03-04
- Target Recruit Count
- 25
- Registration Number
- NCT00005108
- Locations
- 🇺🇸
National Heart, Lung and Blood Institute (NHLBI), Bethesda, Maryland, United States
The Effects of Reproductive Hormones on Mood and Behavior
- Conditions
- Interventions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2022-03-22
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 100
- Registration Number
- NCT00001322
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
The Role of Hormones in Postpartum Mood Disorders
- Conditions
- Interventions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 100
- Registration Number
- NCT00001481
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Women's Estrogen/Progestin Lipid Lowering Hormone Atherosclerosis Regression Trial (WELL-HART)
- Conditions
Drug Development Updates
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