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Autologous tumor lysate-loaded dendritic cell vaccination enhances antitumor immunity by activating T-cell responses against glioblastoma.
Diakonos Oncology has secured $11.4 million in seed funding to advance its dendritic cell vaccine (DCV) candidate, DOC1021, into a Phase II clinical trial for glioblastoma (GBM).
A phase one study of a dendritic cell vaccine combined with intensified temozolomide showed promising survival benefits in glioblastoma patients.