Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension, dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.
Phenylephrine was granted FDA approval in 1939.
Phenylephrine is available in various drug formulations, which have different indications. Phenylephrine injections are indicated to treat hypotension caused by shock or anesthesia. The ophthalmic formulation is indicated to induce mydriasis and conjunctival vasoconstriction. The intranasal formulation is used to treat congestion, and a topical formulation ...
Northwestern University, Chicago, Illinois, United States
Northwestern Memorial Hospital, Chicago, Illinois, United States
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Mount Sinai Hospital, Toronto, Ontario, Canada
Rikshospitalet-Radiumhospitalet HF, Oslo, Norway
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