MedPath

Danvatirsen

Generic Name
Danvatirsen
Drug Type
Biotech
CAS Number
1402357-06-5
Unique Ingredient Identifier
31N550RD05
Background

Danvatirsen is under investigation in clinical trial NCT03334617 (Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.).

AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites

Phase 2
Terminated
Conditions
Ascites
Gastrointestinal Neoplasms
Ovarian Cancer
Ovarian Neoplasms
Gastrointestinal Cancer
Interventions
First Posted Date
2015-04-16
Last Posted Date
2017-05-15
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
1
Registration Number
NCT02417753
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

A Phase I/Ib Study of AZD9150 (ISIS-STAT3Rx) in Patients With Advanced/Metastatic Hepatocellular Carcinoma

Phase 1
Completed
Conditions
Hepatocellular Carcinoma Metastatic
Advanced Adult Hepatocellular Carcinoma
Interventions
First Posted Date
2013-04-25
Last Posted Date
2017-03-06
Lead Sponsor
AstraZeneca
Target Recruit Count
58
Registration Number
NCT01839604
Locations
🇨🇳

Research Site, Taipei, Taiwan

Phase 1/2, Open-label, Dose-escalation Study of IONIS-STAT3Rx, Administered to Patients With Advanced Cancers

Phase 1
Completed
Conditions
DLBCL
Advanced Cancers
Lymphoma
Interventions
First Posted Date
2012-03-26
Last Posted Date
2018-06-25
Lead Sponsor
Ionis Pharmaceuticals, Inc.
Target Recruit Count
64
Registration Number
NCT01563302
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Yale Cancer Center, New Haven, Connecticut, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 6 locations
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