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Ombitasvir/Paritaprevir/Ritonavir

Generic Name
Ombitasvir/Paritaprevir/Ritonavir
Indication

用于治疗成人基因1型慢性丙型肝炎,包括无肝硬化或伴代偿期肝硬化的患者。该治疗方案是全口服的、无干扰素、可联合或不联合利巴韦林。

Bioavailability of ABT-450 and ABT-267 With Ritonavir

Phase 1
Completed
Conditions
Absolute Bioavailability
Interventions
First Posted Date
2014-02-03
Last Posted Date
2014-02-19
Lead Sponsor
AbbVie
Target Recruit Count
16
Registration Number
NCT02052362
Locations
🇬🇧

Site Reference ID/Investigator# 118615, Nottingham, United Kingdom

Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection

Phase 3
Completed
Conditions
Chronic Hepatitis C Infection
Interventions
First Posted Date
2013-12-30
Last Posted Date
2018-06-06
Lead Sponsor
AbbVie
Target Recruit Count
363
Registration Number
NCT02023099

Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT- 267 (ABT-450/r/ABT-267) in Japanese Adults With Genotype 2 Chronic Hepatitis C Virus (HCV) Infection

Phase 3
Completed
Conditions
Hepatitis C Virus
Interventions
First Posted Date
2013-12-30
Last Posted Date
2021-07-30
Lead Sponsor
AbbVie
Target Recruit Count
171
Registration Number
NCT02023112

A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 Coinfection

Phase 2
Completed
Conditions
Hepatitis C Virus Infection
Chronic Hepatitis C
Compensated Cirrhosis and Non-cirrhotics
Human Immunodeficiency Virus Infection
Interventions
First Posted Date
2013-09-11
Last Posted Date
2021-07-12
Lead Sponsor
AbbVie
Target Recruit Count
318
Registration Number
NCT01939197

An Open-label, Single Arm, Phase 2 Study to Evaluate ABT-450/r/ABT-267 and ABT-333 With Ribavirin (RBV) in Adults With Genotype 1 HCV Infection Taking Methadone or Buprenorphine

Phase 2
Completed
Conditions
Chronic Hepatitis C Infection
Chronic Hepatitis C
Interventions
First Posted Date
2013-07-30
Last Posted Date
2018-05-30
Lead Sponsor
AbbVie
Target Recruit Count
38
Registration Number
NCT01911845

A Study to Evaluate Chronic Hepatitis C Infection in Adult Transplant Recipients

First Posted Date
2013-02-04
Last Posted Date
2017-11-07
Lead Sponsor
AbbVie
Target Recruit Count
129
Registration Number
NCT01782495
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