Sodium bicarbonate
- Generic Name
- Sodium bicarbonate
- Brand Names
- Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- CHNaO3
- CAS Number
- 144-55-8
- Unique Ingredient Identifier
- 8MDF5V39QO
- Background
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
- Indication
Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...
- Associated Conditions
- Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
- Associated Therapies
- Bowel preparation therapy
Effect of Different Approaches of Delivering Local Dental Anesthesia on Pain Perception in Children.
- First Posted Date
- 2022-04-21
- Last Posted Date
- 2022-04-29
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 80
- Registration Number
- NCT05338983
- Locations
- 🇪🇬
Faculty of Dentistry, Mansoura, Egypt
Reducing Dietary Acid with Food Versus Oral Alkali in People with Chronic Kidney Disease (ReDACKD)
- Conditions
- Interventions
- First Posted Date
- 2021-11-09
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Dylan MacKay
- Target Recruit Count
- 40
- Registration Number
- NCT05113641
- Locations
- 🇨🇦
Seven Oaks General Hospital Chronic Disease Innovation Centre, Winnipeg, Manitoba, Canada
🇨🇦Chronic Kidney Disease (Renal) ClinicQEII - Dickson Building, Halifax, Nova Scotia, Canada
Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2021-08-16
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 120
- Registration Number
- NCT05005793
- Locations
- 🇺🇸
University of Colorado, Aurora, Colorado, United States
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
- Conditions
- Interventions
- First Posted Date
- 2021-07-30
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- University of California, Davis
- Target Recruit Count
- 80
- Registration Number
- NCT04984226
- Locations
- 🇺🇸
University of California Davis Health, Sacramento, California, United States
🇺🇸Vanderbilt University Medical Center, Nashville, Tennessee, United States
Risk Potential for Organ Dysfunction Associated With Sodium Bicarbonate Therapy (SBT) in Critically Ill Patients
- Conditions
- Interventions
- First Posted Date
- 2021-07-07
- Last Posted Date
- 2021-07-07
- Lead Sponsor
- Peking University Third Hospital
- Target Recruit Count
- 664
- Registration Number
- NCT04953013
- Locations
- 🇨🇳
Critical Care Medicine Department, Beijing, Beijing, China
Urine Alkalinisation in COVID-19
- Conditions
- Interventions
- First Posted Date
- 2021-03-19
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Guy's and St Thomas' NHS Foundation Trust
- Target Recruit Count
- 80
- Registration Number
- NCT04806061
- Locations
- 🇬🇧
Guy's & St Thomas Foundation Hospital, London, United Kingdom
🇬🇧Guy's & St Thomas Hospital, London, United Kingdom
Comparison of Effectiveness and Complications of Catheter Lock Solutions in Non-tunneled Hemodialysis Catheters
- Conditions
- Interventions
- First Posted Date
- 2021-02-26
- Last Posted Date
- 2023-06-13
- Lead Sponsor
- Zonguldak Ataturk State Hospital
- Target Recruit Count
- 441
- Registration Number
- NCT04772209
- Locations
- 🇹🇷
Cumhuriyet University Hospital, Sivas, TN, Turkey
🇹🇷Zonguldak ataturk state hospital, Zonguldak, TN, Turkey
Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet
- Conditions
- Interventions
- First Posted Date
- 2020-12-03
- Last Posted Date
- 2024-03-01
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 15
- Registration Number
- NCT04651088
- Locations
- 🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Injection Site Pain Botulinum Toxin Reconstituted in NS With and Without Sodium Bicarbonate
- First Posted Date
- 2020-10-08
- Last Posted Date
- 2020-10-08
- Lead Sponsor
- King Abdulaziz Medical City
- Target Recruit Count
- 30
- Registration Number
- NCT04579419
- Locations
- 🇸🇦
King Abdulaziz Medical City, Riyadh, Saudi Arabia
Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization
- Conditions
- Interventions
- First Posted Date
- 2020-08-28
- Last Posted Date
- 2023-12-22
- Lead Sponsor
- West Virginia University
- Target Recruit Count
- 3
- Registration Number
- NCT04530448
- Locations
- 🇺🇸
WVU Medicine Heart & Vascular Institute, Morgantown, West Virginia, United States
Drug Development Updates
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