Sodium bicarbonate
- Generic Name
- Sodium bicarbonate
- Brand Names
- Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- CHNaO3
- CAS Number
- 144-55-8
- Unique Ingredient Identifier
- 8MDF5V39QO
- Background
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
- Indication
Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...
- Associated Conditions
- Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
- Associated Therapies
- Bowel preparation therapy
Use of Sodium Bicarbonate As Prophylaxis for Kidney Damage in Patients with Heatstroke
- Conditions
- Interventions
- First Posted Date
- 2024-10-02
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Hospital General de Mexicali
- Target Recruit Count
- 1
- Registration Number
- NCT06622525
- Locations
- 🇲🇽
Hospital General de Mexicali, Mexicali, Baja California, Mexico
Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
- Conditions
- Interventions
- First Posted Date
- 2024-03-28
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- University of California, Irvine
- Target Recruit Count
- 100
- Registration Number
- NCT06335537
- Locations
- 🇺🇸
University of California, Irvine Medical Center, Orange, California, United States
A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants
- Conditions
- Interventions
- First Posted Date
- 2024-01-02
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 50
- Registration Number
- NCT06186622
- Locations
- 🇺🇸
Fortrea Clinical Research Unit Inc., Dallas, Texas, United States
Combination of Buffered Anesthetic to Treat Mandibular Molars
- Conditions
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 60
- Registration Number
- NCT06047366
- Locations
- 🇺🇸
ndiana University School of Dentistry Graduate Endodontics Dept., Indianapolis, Indiana, United States
Neurovascular Regulation During Exercise in Humans With Chronic Kidney Disease: Sympatholysis in CKD
- Conditions
- Interventions
- First Posted Date
- 2023-07-03
- Last Posted Date
- 2023-07-03
- Lead Sponsor
- Emory University
- Target Recruit Count
- 156
- Registration Number
- NCT05928936
- Locations
- 🇺🇸
Emory Clinic, Atlanta, Georgia, United States
🇺🇸Atlanta VA Medical Center, Decatur, Georgia, United States
Is Hyaluronic Acid Gel Effective on Oral Mucositis in Children Who Receiving Chemotherapy
- First Posted Date
- 2023-04-18
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- Yuzuncu Yıl University
- Target Recruit Count
- 40
- Registration Number
- NCT05818007
- Locations
- 🇹🇷
Yuzuncu Yil University, Van, Turkey
SAINT: Safe Induction of Labor Trial
- Conditions
- Interventions
- First Posted Date
- 2023-02-09
- Last Posted Date
- 2024-04-04
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 3000
- Registration Number
- NCT05719467
- Locations
- 🇳🇴
Akershus University Hospital, Lørenskog, Norway
🇳🇴Oslo University Hospital Ullevål, Oslo, Norway
🇳🇴The University Hospital of North Norway, Tromsø, Norway
SODium BICarbonate for Metabolic Acidosis in the ICU
- Conditions
- Interventions
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2024-06-21
- Target Recruit Count
- 500
- Registration Number
- NCT05697770
- Locations
- 🇳🇿
Auckland City Hospital, Auckland, New Zealand
🇦🇺Canberra Hospital, Garran, Australian Capital Territory, Australia
🇦🇺Mater Hospital, South Brisbane, Queensland, Australia
Sodium Bicarbonate for Acute Peripheral Vertigo
- Conditions
- Interventions
- First Posted Date
- 2023-01-09
- Last Posted Date
- 2023-07-12
- Lead Sponsor
- National Taiwan University Hospital
- Target Recruit Count
- 225
- Registration Number
- NCT05676216
- Locations
- 🇨🇳
National Taiwan University Yunlin Branch, Yunlin County, Taiwan
Bicarbonate for In-Hospital Cardiac Arrest
- First Posted Date
- 2022-10-03
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Lars Wiuff Andersen
- Target Recruit Count
- 778
- Registration Number
- NCT05564130
- Locations
- 🇩🇰
Nykøbing Falster Hospital, Nykøbing Falster, Denmark
🇩🇰Hospital of Southern Jutland - Aabenraa, Aabenraa, Denmark
🇩🇰Copenhagen University Hospital - Herlev, Herlev, Denmark
Drug Development Updates
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