Sodium bicarbonate

Generic Name
Sodium bicarbonate
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
Drug Type
Small Molecule
Chemical Formula
CHNaO3
CAS Number
144-55-8
Unique Ingredient Identifier
8MDF5V39QO
Background

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Indication

Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...

Associated Conditions
Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
Associated Therapies
Bowel preparation therapy

Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-acetylcysteine

Not Applicable
Completed
Conditions
First Posted Date
2006-07-18
Last Posted Date
2010-02-25
Lead Sponsor
Shaare Zedek Medical Center
Target Recruit Count
250
Registration Number
NCT00353340
Locations
🇮🇱

Shaare Zmc, Jerusalem, Israel

Sodium Bicarbonate in Cardiac Surgery

First Posted Date
2006-06-06
Last Posted Date
2009-07-07
Lead Sponsor
Austin Health
Target Recruit Count
100
Registration Number
NCT00334191
Locations
🇦🇺

Austin Hospital, Melbourne, Victoria, Australia

Trial for Prevention of Contrast Nephropathy With Sodium Bicarbonate

First Posted Date
2006-04-07
Last Posted Date
2015-03-11
Lead Sponsor
Kaiser Permanente
Target Recruit Count
300
Registration Number
NCT00312117
Locations
🇺🇸

Kaiser Permanente Medical Center, Los Angeles, California, United States

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