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Sodium bicarbonate

Generic Name
Sodium bicarbonate
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
Drug Type
Small Molecule
Chemical Formula
CHNaO3
CAS Number
144-55-8
Unique Ingredient Identifier
8MDF5V39QO

Overview

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Background

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

Indication

Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments.

Associated Conditions

  • Barbiturate intoxication
  • Breast Cancer
  • Constipation
  • Dental Decay
  • Duodenal Ulcer
  • Dyspepsia
  • Gastro-esophageal Reflux Disease (GERD)
  • Gingival Bleeding
  • Heartburn
  • Helicobacter Infections
  • Hyperkalemia
  • Ischaemia
  • Metabolic Acidosis
  • Myocardial Infarction
  • Plaque, Dental
  • Pruritis of the skin
  • Skin Irritation
  • Upper GI Bleeding
  • Upset stomach
  • Zollinger-Ellison Syndrome
  • Abdominal bloating
  • Benign, active Gastric Ulcer
  • Methyl alcohol poisoning
  • Prophylaxis of Contrast-induced nephropathy
  • Salicylate poisoning
  • Severe Diarrhea
  • Swelling of the gums

FDA Approved Products

ZEGERID
Manufacturer:Santarus, Inc..
Route:ORAL
Strength:1680 mg in 1 1
Approved: 2023/07/19
NDC:68012-052
Omeprazole/Sodium Bicarbonate
Manufacturer:Strides Pharma Science Limited
Route:ORAL
Strength:1680 mg in 1720 mg
Approved: 2023/09/21
NDC:64380-183
omeprazole and sodium bicarbonate
Manufacturer:Zydus Lifesciences Limited
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2023/09/27
NDC:70771-1101
omeprazole and sodium bicarbonate
Manufacturer:Zydus Lifesciences Limited
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2023/09/27
NDC:70771-1102
Omeprazole and Sodium Bicrabonate
Manufacturer:Dr.Reddy's Laboratories Limited
Route:ORAL
Strength:1100 mg in 1 1
Approved: 2022/03/20
NDC:55111-364

Singapore Approved Products

BICART POWDER FOR HAEMODIALYSIS
Manufacturer:Gambro Dasco S.p.A
Form:POWDER, FOR SOLUTION
Strength:100%
Online:Yes
Approved: 1991/07/03
Approval:SIN06382P
ALKA-SELTZER TABLET (Lemon Flavour)
Manufacturer:BAYER DE MEXICO SA DE CV
Form:TABLET
Strength:1737 mg
Online:Yes
Approved: 1996/04/04
Approval:SIN08632P
KAOMIX ORAL MIXTURE
Manufacturer:ICM PHARMA PTE. LTD.
Form:SUSPENSION
Strength:5% w/v
Online:Yes
Approved: 1996/07/03
Approval:SIN08787P
AROMAG ANTACID MIXTURE
Manufacturer:ICM PHARMA PTE. LTD.
Form:SUSPENSION
Strength:5% w/v
Online:Yes
Approved: 1996/07/03
Approval:SIN08784P
SODIUM BICARBONATE CAPSULE 500 mg
Manufacturer:BEACONS PHARMACEUTICALS PTE LTD
Form:CAPSULE
Strength:500 mg
Online:Yes
Approved: 1991/02/18
Approval:SIN05414P

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