Penequinine, Penehyclidine
- Generic Name
- Penequinine, Penehyclidine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C20H29NO2
- CAS Number
- 87827-02-9
- Unique Ingredient Identifier
- 353CX8CSHD
- Background
Penequinine, Penehyclidine is under investigation in clinical trial NCT02644876 (Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications).
- Indication
⑴麻醉前给药以抑制涎腺和气道腺体分泌。
⑵用于有机磷毒物中毒急救治疗和中毒后期或胆碱酯酶老化后维持阿托品化。但单独应用疗效差，应与酶重活化剂联合应用。
- Associated Conditions
- -
- Associated Therapies
- -
Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia
Phase 4
Recruiting
- Conditions
- Respiratory HypersensitivityPerioperative Respiratory Adverse EventsAnticholinergicsInhalation Therapy; ComplicationsHigh Risk
- Interventions
- Drug: Penehyclidine hydrochlorideDrug: Normal Saline
- First Posted Date
- 2024-10-03
- Last Posted Date
- 2025-01-03
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 204
- Registration Number
- NCT06624696
- Locations
- 🇨🇳
Shenzhen Eye Hospital, Shenzhen, Guangdong, China
🇨🇳Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China
Penehyclidine for PONV Prophylaxis After Strabismus Surgery
- First Posted Date
- 2019-08-13
- Last Posted Date
- 2019-12-17
- Lead Sponsor
- The First Affiliated Hospital with Nanjing Medical University
- Target Recruit Count
- 228
- Registration Number
- NCT04054479
- Locations
- 🇨🇳
The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
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