Mycophenolic acid

Generic Name
Mycophenolic acid
Brand Names
Myfortic
Drug Type
Small Molecule
Chemical Formula
C17H20O6
CAS Number
24280-93-1
Unique Ingredient Identifier
HU9DX48N0T
Background

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties.. Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacroli...

Indication

Mycophenolic acid is an antimetabolite immunosuppressant indicated for prophylaxis of organ rejection in adult patients receiving kidney transplants and in pediatric patients at least 5 years of age and older who are at least 6 months post kidney transplant. Mycophenolic acid is used in combination with cyclosporine and corticosteroids.

Associated Conditions
Kidney Transplant Rejection
Associated Therapies
-

Freedom Study: Myfortic in Kidney Transplant Patients

Phase 3
Completed
Conditions
First Posted Date
2005-01-13
Last Posted Date
2011-01-31
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
342
Registration Number
NCT00101738
Locations
🇬🇧

Queen Elizabeth Medical Centre, Edgbaston, Birmingham, United Kingdom

🇦🇺

Royal Melbourne Hospital, Parkville, Victoria, Australia

🇬🇧

Walsgrave Hospital NHS Trust, Walsgrave, Coventry, United Kingdom

and more 41 locations
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