Sevoflurane
- Generic Name
- Sevoflurane
- Brand Names
- Sevorane, Sojourn, Ultane
- Drug Type
- Small Molecule
- Chemical Formula
- C4H3F7O
- CAS Number
- 28523-86-6
- Unique Ingredient Identifier
- 38LVP0K73A
- Background
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996. Sevoflurane is three times more potent than desflurane, but has lower potency compared to halothane and isoflurane. Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity. Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.
- Indication
Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Small Doses of Dexmedetomidine for Emergence Agitation
- Conditions
- Interventions
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2014-06-23
- Lead Sponsor
- Tang-Du Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT02169843
- Locations
- 🇨🇳
Tangdu Hospital, Xi'an, Shanxi, China
Inflammatory Response Secondary Using Intravenous Anesthesia Versus Inhalation Anesthesia With Halogenated Agents
- First Posted Date
- 2014-06-20
- Last Posted Date
- 2016-04-06
- Lead Sponsor
- Hospital General Universitario Gregorio Marañon
- Target Recruit Count
- 180
- Registration Number
- NCT02168751
- Locations
- 🇪🇸
Anesthesiology Department Hospital GU Gregorio Mrañón, Madrid, Spain
Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)
- Conditions
- Interventions
- First Posted Date
- 2014-06-18
- Last Posted Date
- 2016-03-04
- Lead Sponsor
- University Hospital, Clermont-Ferrand
- Target Recruit Count
- 50
- Registration Number
- NCT02166853
- Locations
- 🇫🇷
CHU Clermont-Ferrand, Clermont-Ferrand, France
Different Hemostasis According to the Anesthetic Agents
- Conditions
- Interventions
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2014-05-30
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 66
- Registration Number
- NCT02151305
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of
Neural Mechanisms of Sevoflurane Induced Anesthesia: an EEG fMRI Study in Healthy Volunteers
- First Posted Date
- 2014-05-29
- Last Posted Date
- 2014-05-29
- Lead Sponsor
- Technical University of Munich
- Target Recruit Count
- 20
- Registration Number
- NCT02149927
- Locations
- 🇩🇪
Klinikum rechts der Isar, Munich, Bayern, Germany
Postoperative Sleep Quality of Patients Anesthesia With Propofol or Sevoflurane Undergoing Thyroidectomy
- First Posted Date
- 2014-05-26
- Last Posted Date
- 2016-01-29
- Lead Sponsor
- China Medical University, China
- Target Recruit Count
- 124
- Registration Number
- NCT02146976
- Locations
- 🇨🇳
the First Hospital of China Medical University, Shenyang, Liaoning, China
Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery
- Conditions
- Interventions
- First Posted Date
- 2014-05-13
- Last Posted Date
- 2018-01-18
- Lead Sponsor
- Konkuk University Medical Center
- Target Recruit Count
- 2
- Registration Number
- NCT02136979
- Locations
- 🇰🇷
Konkuk University Medical Center, Seoul, Korea, Republic of
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
- First Posted Date
- 2014-05-08
- Last Posted Date
- 2014-05-08
- Lead Sponsor
- Negovsky Reanimatology Research Institute
- Target Recruit Count
- 130
- Registration Number
- NCT02133638
- Locations
- 🇷🇺
Medical center of the Main Administration for Service to the Diplomatic Corps, Moscow, Russian Federation
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
- Conditions
- Interventions
- First Posted Date
- 2014-04-11
- Last Posted Date
- 2019-07-23
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 6
- Registration Number
- NCT02111447
- Locations
- 🇺🇸
Women and Chidren's Hospital Of Buffalo, Buffalo, New York, United States
Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.
- First Posted Date
- 2014-04-08
- Last Posted Date
- 2018-06-12
- Lead Sponsor
- Tao Zhang
- Target Recruit Count
- 68
- Registration Number
- NCT02107170
- Locations
- 🇨🇳
First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China
Drug Development Updates
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