Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural similarities to glucose and are involved in cellular signaling. It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate into disease conditions. Inositol can be found as an ingredient of OTC products by Health Canada but all current product whose main ingredient is inositol are discontinued. By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized as safe (GRAS).
Inositol may be used in food without any limitation. As a drug, inositol is used as a nutrient supplement in special dietary foods and infant formula. As it presents a relevant role in ensuring oocyte fertility, inositol has been studied for its use in the management of polycystic ovaries. Inositol is also being researched for the treatment of diabetes, prevention of metabolic syndrome, aid agent for weight loss, treatment of depression, psychiatric disorder and anxiety disorder and for prevention of cancer.
Beni-suef university Hospital, Banī Suwayf, Beni Suef, Egypt
IRCCS - Istituto Oncologico"Giovanni PaoloII", Bari, Italy
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
Hospital Das Clinicas - Fmusp, Sao Paulo, Brazil
University Hospital, Ghent, Belgium
American University of Beirut Medical Center, Beirut, Lebanon
Rashid Latif Medical College, Lahore, Punjab, Pakistan
Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Universitair Ziekenhuis Brussel, Brussels, Belgium
American University of Beirut Medical Center, Beirut, Lebanon
Child and Adolescent Bipolar Services-WPIC Bellefield, Pittsburgh, Pennsylvania, United States
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