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Inositol

Generic Name
Inositol
Brand Names
Alertonic
Drug Type
Small Molecule
Chemical Formula
C6H12O6
CAS Number
87-89-8
Unique Ingredient Identifier
4L6452S749
Background

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural similarities to glucose and are involved in cellular signaling. It is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate into disease conditions. Inositol can be found as an ingredient of OTC products by Health Canada but all current product whose main ingredient is inositol are discontinued. By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized as safe (GRAS).

Indication

Inositol may be used in food without any limitation. As a drug, inositol is used as a nutrient supplement in special dietary foods and infant formula. As it presents a relevant role in ensuring oocyte fertility, inositol has been studied for its use in the management of polycystic ovaries. Inositol is also being researched for the treatment of diabetes, prevention of metabolic syndrome, aid agent for weight loss, treatment of depression, psychiatric disorder and anxiety disorder and for prevention of cancer.

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

Not Applicable
Completed
Conditions
Bipolar Disorder
First Posted Date
2001-03-15
Last Posted Date
2007-05-04
Lead Sponsor
National Institute of Mental Health (NIMH)
Target Recruit Count
5000
Registration Number
NCT00012558
Locations
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Case Western Reserve University, Cleveland, Ohio, United States

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University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, United States

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University of Pittsburgh, Pittsburgh, Pennsylvania, United States

and more 8 locations
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