Ibritumomab tiuxetan
- Generic Name
- Ibritumomab tiuxetan
- Brand Names
- Zevalin
- Drug Type
- Biotech
- CAS Number
- 206181-63-7
- Unique Ingredient Identifier
- 4Q52C550XK
Overview
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
Background
Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.
Indication
For treatment of non-Hodgkin's lymphoma
Associated Conditions
- Follicular Non-Hodgkin's Lymphoma
- Follicular Non-Hodgkin's Lymphoma Refractory
- Relapsed follicular B-cell non-Hodgkin's lymphoma
Clinical Trials
FDA Approved Products
Singapore Approved Products
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