Heparin
- Generic Name
- Heparin
- Brand Names
- Heparin Leo
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9005-49-6
- Unique Ingredient Identifier
- T2410KM04A
- Background
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (fac...
- Indication
Unfractionated heparin is indicated for prophylaxis and treatment of venous thrombosis and its extension, prevention of post-operative deep venous thrombosis and pulmonary embolism and prevention of clotting in arterial and cardiac surgery. In cardiology, it is used to prevent embolisms in patients with atrial fibrillation and as an adjunct antithrombin ther...
- Associated Conditions
- Blunt Injury, Clotting, Coagulopathy, Consumption, Contusions, Deep vein thrombosis postoperative, Disseminated Intravascular Coagulation (DIC), External Hemorrhoid, Inflammation, Inflammatory, non-infectious pruritic dermatosis, Interstitial Cystitis, Post procedural pulmonary embolism, Pulmonary Embolism, ST Segment Elevation Myocardial Infarction (STEMI), Sprains, Thromboembolism, Unstable Angina Pectoris, Venous Thrombosis (Disorder), Hematomas, Peripheral arterial embolism, Thromboembolic phenomena, Varicosities of the great saphenous vein
- Associated Therapies
- Circulation, Extracorporeal, Dialysis therapy, Transfusions, Maintenance of patency of IV injection devices
Coronary Arteriogenetic Heparinized Exercise
- Conditions
- Interventions
- First Posted Date
- 2017-11-22
- Last Posted Date
- 2020-05-13
- Lead Sponsor
- Clinical Centre of Serbia
- Target Recruit Count
- 32
- Registration Number
- NCT03350737
- Locations
- 🇷🇸
Clinical Centre of Serbia, Belgrade, Serbia
Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMO
- Conditions
- Interventions
- First Posted Date
- 2017-10-23
- Last Posted Date
- 2023-01-31
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT03318393
- Locations
- 🇺🇸
Children's Medical Center, Dallas, Texas, United States
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2
- Conditions
- Interventions
- First Posted Date
- 2017-10-11
- Last Posted Date
- 2017-10-11
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 408
- Registration Number
- NCT03306836
- Locations
- 🇨🇳
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China
Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-10-05
- Last Posted Date
- 2023-03-10
- Lead Sponsor
- Laval University
- Target Recruit Count
- 410
- Registration Number
- NCT03302195
- Locations
- 🇨🇦
Hopital Laval, Quebec City, Quebec, Canada
The Effect of Heparinization Due to LBW
- First Posted Date
- 2017-04-13
- Last Posted Date
- 2017-04-14
- Lead Sponsor
- Adiyaman University Research Hospital
- Target Recruit Count
- 50
- Registration Number
- NCT03113708
Timing of VTE Prophylaxis in TBI
- Conditions
- Interventions
- First Posted Date
- 2017-03-16
- Last Posted Date
- 2019-08-16
- Lead Sponsor
- Loyola University
- Registration Number
- NCT03081169
- Locations
- 🇺🇸
Loyola University Medical Center, Maywood, Illinois, United States
The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss
- Conditions
- Interventions
- First Posted Date
- 2016-12-13
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Shanghai First Maternity and Infant Hospital
- Target Recruit Count
- 500
- Registration Number
- NCT02990403
- Locations
- 🇨🇳
Shanghai first Maternity and Infant health hospital, Tong Ji University, Shanghai, China
Diagnosis and Treatment Strategy of Recurrent Spontaneous Abortion Associated With Thrombophilla
- First Posted Date
- 2016-12-08
- Last Posted Date
- 2016-12-09
- Lead Sponsor
- Shanghai First Maternity and Infant Hospital
- Target Recruit Count
- 600
- Registration Number
- NCT02986594
- Locations
- 🇨🇳
Shanghai first Maternity and Infant health hospital, Tong Ji University, Shanghai, China
LMWH Infusion as Anticoagulation for Home HD
- First Posted Date
- 2016-11-08
- Last Posted Date
- 2016-11-08
- Lead Sponsor
- Alice Ho Miu Ling Nethersole Hospital
- Target Recruit Count
- 12
- Registration Number
- NCT02957877
- Locations
- 🇭🇰
Alice Ho Miu Ling Nethersole Hospital, Hong Kong, Hong Kong
Preoperative Administration of Heparin as Thromboprophylaxis in Major Thoracic Surgery
- First Posted Date
- 2016-10-21
- Last Posted Date
- 2016-10-24
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 2000
- Registration Number
- NCT02940444
- Locations
- 🇨🇳
Department of thoracic surgery, west china hospital, sichuan university, Chengdu, Sichuan, China
Drug Development Updates
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