Memantine
- Generic Name
- Memantine
- Brand Names
- Axura, Ebixa, Marixino, Namenda, Namenda 49 Titration Pack, Namzaric, Nemdatine, Memantine Mylan, Memantine ratiopharm, Memantine Merz, Marixino (previously Maruxa), Memantine Accord, Memantine LEK
- Drug Type
- Small Molecule
- Chemical Formula
- C12H21N
- CAS Number
- 19982-08-2
- Unique Ingredient Identifier
- W8O17SJF3T
- Background
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's disease . ...
- Indication
Memantine is used to manage moderate to severe Alzheimer's dementia .
...
- Associated Conditions
- Alzheimer's Disease (AD), Moderate to Severe Alzheimer's Disease, Mild Vascular dementia, Moderate Alzheimer's Type Dementia, Moderate Vascular dementia, Severe Alzheimer's Type Dementia
- Associated Therapies
- -
Evaluation of the Safety and Efficacy of Memantine as Adjunctive Treatment in Schizophrenia Patients
- Conditions
- First Posted Date
- 2004-12-02
- Last Posted Date
- 2012-03-05
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 138
- Registration Number
- NCT00097942
- Locations
- 🇺🇸
Metropolitan Psychiatric Center, St. Louis, Missouri, United States
🇺🇸CBH Health, LLC, Rockville, Maryland, United States
🇺🇸Dartmouth Hitchcock Medical School, Lebanon, New Hampshire, United States
Clinical Trial of Memantine for Major Depression
- Conditions
- First Posted Date
- 2002-06-24
- Last Posted Date
- 2008-03-04
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 112
- Registration Number
- NCT00040261
- Locations
- 🇺🇸
National Institute of Mental Health (NIMH), Bethesda, Maryland, United States
A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC)
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2013-06-10
- Target Recruit Count
- 120
- Registration Number
- NCT00000867
- Locations
- 🇺🇸
Washington U CRS, St. Louis, Missouri, United States
🇺🇸UCLA CARE Center CRS, Los Angeles, California, United States
🇺🇸Beth Israel Med. Ctr. (Mt. Sinai), New York, New York, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.