Zucapsaicin
- Generic Name
- Zucapsaicin
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H27NO3
- CAS Number
- 25775-90-0
- Unique Ingredient Identifier
- 15OX67P384
- Background
Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain. It is a modulator of transient receptor potential cation channel subfamily V member 1 (TRPV-1), also known as the vanilloid or capsaicin receptor 1, that reduces pain and improves articular functions. Zucapsaicin has also been...
- Indication
Indicated to be used in conjunction with oral COX-2 inhibitors or NSAIDs for the relief of severe pain in adult patients with osteoarthritis of the knee, not controlled with oral COX-2 inhibitors or NSAIDs alone, for a duration of no more than three months.
- Associated Conditions
- Severe Pain
- Associated Therapies
- -
Oral Civamide Safety, Tolerability First in Human Study
- First Posted Date
- 2008-12-04
- Last Posted Date
- 2011-06-10
- Lead Sponsor
- Winston Laboratories
- Target Recruit Count
- 12
- Registration Number
- NCT00802217
- Locations
- 🇺🇸
Parexel International, Inc., Baltimore, Maryland, United States
Civamide Patch Safety, Tolerability and PK Study
- First Posted Date
- 2008-09-25
- Last Posted Date
- 2011-06-10
- Lead Sponsor
- Winston Laboratories
- Target Recruit Count
- 39
- Registration Number
- NCT00758433
- Locations
- 🇺🇸
International Research Services, Inc., Port Chester, New York, United States
Civamide in OA of the Knee(s)
- Conditions
- First Posted Date
- 2004-02-18
- Last Posted Date
- 2011-06-08
- Lead Sponsor
- Winston Laboratories
- Target Recruit Count
- 351
- Registration Number
- NCT00077935
- Locations
- 🇺🇸
NC Arthritis and Allergy Care Center, Raleigh, North Carolina, United States
🇺🇸Chesapeake Medical Research, LLC, Baltimore, Maryland, United States
🇺🇸University Hospitals of Cleveland, Beachwood, Ohio, United States
Drug Development Updates
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