Fluticasone furoate

Generic Name
Fluticasone furoate
Brand Names
Arnuity Ellipta, Avamys, Breo Ellipta, Flonase Sensimist, Trelegy Ellipta, Veramyst
Drug Type
Small Molecule
Chemical Formula
C27H29F3O6S
CAS Number
397864-44-7
Unique Ingredient Identifier
JS86977WNV
Background

Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications. Fluticasone furoate was first approved in 2007.

Indication

Fluticasone furoate is indicated for once-daily maintenance (i.e. prophylactic) treatment of asthma in patients ≥5 years old. Fluticasone furoate is available in two combination medications - one in combination with vilanterol and one in combination with both vilanterol and umeclidinium- which are both indicated for the management of chronic obstructive pulm...

Associated Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Perennial Allergy, Seasonal Allergies
Associated Therapies
-

Effect of Inhaled Fluticasone Furoate on Short-term Growth in Paediatric Subjects With Asthma

First Posted Date
2015-07-20
Last Posted Date
2017-11-17
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
60
Registration Number
NCT02502734
Locations
🇩🇰

GSK Investigational Site, Randers, Denmark

A Study to Compare the Efficacy of Fluticasone Furoate/Vilanterol Inhalation Powder With Usual Inhaled Corticosteroids (ICS)/Long Acting Beta Agonists (LABA) in Persistent Asthma

First Posted Date
2015-05-18
Last Posted Date
2019-01-14
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
423
Registration Number
NCT02446418
Locations
🇩🇪

GSK Investigational Site, Magdeburg, Germany

Study to Determine the Pharmacokinetics of GSK961081 and Fluticasone Furoate When Administered Alone or in Combination

First Posted Date
2014-02-17
Last Posted Date
2017-05-15
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
48
Registration Number
NCT02064504
Locations
🇦🇺

GSK Investigational Site, Randwick, New South Wales, Australia

RELOVAIR® Lung Deflation Study

First Posted Date
2012-09-25
Last Posted Date
2016-10-27
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
45
Registration Number
NCT01691885
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

Study FFR116364, a Placebo-controlled Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis

First Posted Date
2012-06-28
Last Posted Date
2017-01-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
261
Registration Number
NCT01630135
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

Study FFR116365, an Open-label Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis

Phase 3
Completed
Conditions
Interventions
First Posted Date
2012-06-19
Last Posted Date
2017-01-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
61
Registration Number
NCT01622231
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

A Dose-ranging Study of Fluticasone Furoate (FF)

First Posted Date
2012-03-26
Last Posted Date
2017-05-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
597
Registration Number
NCT01563029
Locations
🇺🇦

GSK Investigational Site, Zaporizhia, Ukraine

Inhaled Fluticasone Furoate/Vilanterol Safety and Tolerability, PK and PD Study

First Posted Date
2011-10-17
Last Posted Date
2017-01-11
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
26
Registration Number
NCT01453023
Locations
🇺🇸

GSK Investigational Site, Huntington Beach, California, United States

Evaluating the Efficacy and Safety of Fluticasone Furoate in the Treatment of Asthma in Adults and Adolescents

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-09-12
Last Posted Date
2017-01-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
238
Registration Number
NCT01431950
Locations
🇷🇺

GSK Investigational Site, Pyatigorsk, Russian Federation

Pharmacokinetics and PharmacoDynamics of GW685698 in Paedeatric Asthmatic Patients

Phase 2
Completed
Conditions
Interventions
First Posted Date
2011-04-11
Last Posted Date
2017-03-23
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
27
Registration Number
NCT01332292
Locations
🇺🇸

GSK Investigational Site, Medford, Oregon, United States

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