Fluticasone furoate

Generic Name
Fluticasone furoate
Brand Names
Arnuity Ellipta, Avamys, Breo Ellipta, Flonase Sensimist, Trelegy Ellipta, Veramyst
Drug Type
Small Molecule
Chemical Formula
C27H29F3O6S
CAS Number
397864-44-7
Unique Ingredient Identifier
JS86977WNV
Background

Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications. Fluticasone furoate was first approved in 2007.

Indication

Fluticasone furoate is indicated for once-daily maintenance (i.e. prophylactic) treatment of asthma in patients ≥5 years old. Fluticasone furoate is available in two combination medications - one in combination with vilanterol and one in combination with both vilanterol and umeclidinium- which are both indicated for the management of chronic obstructive pulm...

Associated Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Perennial Allergy, Seasonal Allergies
Associated Therapies
-

Rhinitis, Cognition and Driving Performance

First Posted Date
2011-03-18
Last Posted Date
2013-11-08
Lead Sponsor
Maastricht University Medical Center
Target Recruit Count
22
Registration Number
NCT01318681
Locations
🇳🇱

Maastricht University, Maastricht, Limburg, Netherlands

Study to Evaluate the Effect of Fluticasone Furoate/Vilanterol on Survival in Subjects With Chronic Obstructive Pulmonary Disease

First Posted Date
2011-03-14
Last Posted Date
2018-08-06
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
16568
Registration Number
NCT01313676
Locations
🇻🇳

GSK Investigational Site, Hue, Vietnam

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate and GW642444 Are Processed by the Body in Healthy Subjects

First Posted Date
2011-02-18
Last Posted Date
2017-06-12
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
16
Registration Number
NCT01299558
Locations
🇦🇺

GSK Investigational Site, Randwick, New South Wales, Australia

Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents

First Posted Date
2010-07-12
Last Posted Date
2017-11-09
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
350
Registration Number
NCT01159912
Locations
🇷🇴

GSK Investigational Site, Iasi, Romania

Randomised Study Comparing the Effects of Inhaled FF/GW642444M Combination, FF and GW642444M on an Allergen Induced Asthmatic Response

First Posted Date
2010-05-24
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
27
Registration Number
NCT01128595
Locations
🇸🇪

GSK Investigational Site, Lund, Sweden

Randomised Study Comparing the Effects of Inhaled Fluticasone Furoate (FF)/Vilanterol (VI; GW642444M) Combination and FF on an Allergen Induced Asthmatic Response

First Posted Date
2010-05-24
Last Posted Date
2017-01-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
52
Registration Number
NCT01128569
Locations
🇬🇧

GSK Investigational Site, Manchester, United Kingdom

Asthma Exacerbation Study

First Posted Date
2010-03-15
Last Posted Date
2018-01-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
2020
Registration Number
NCT01086384
Locations
🇺🇦

GSK Investigational Site, Zaporizhia, Ukraine

Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease

First Posted Date
2009-11-16
Last Posted Date
2017-09-13
Lead Sponsor
Johns Hopkins University
Target Recruit Count
7
Registration Number
NCT01013701

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-10-23
Last Posted Date
2017-06-22
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
80
Registration Number
NCT01000597
Locations
🇦🇺

GSK Investigational Site, Randwick, New South Wales, Australia

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