Fluticasone furoate
- Generic Name
- Fluticasone furoate
- Brand Names
- Arnuity Ellipta, Avamys, Breo Ellipta, Flonase Sensimist, Trelegy Ellipta, Veramyst
- Drug Type
- Small Molecule
- Chemical Formula
- C27H29F3O6S
- CAS Number
- 397864-44-7
- Unique Ingredient Identifier
- JS86977WNV
- Background
Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications. Fluticasone furoate was first approved in 2007.
- Indication
Fluticasone furoate is indicated for once-daily maintenance (i.e. prophylactic) treatment of asthma in patients ≥5 years old. Fluticasone furoate is available in two combination medications - one in combination with vilanterol and one in combination with both vilanterol and umeclidinium- which are both indicated for the management of chronic obstructive pulmonary disease (COPD) and for the treatment of asthma in patients ≥18 years old for the vilanterol-umeclidinium-fluticasone product and ≥5 years old for the vilanterol-fluticasone product.
Fluticasone furoate is available over the counter as a nasal spray for the symptomatic treatment of hay fever and other upper respiratory allergies in patients ≥2 years old.
- Associated Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Perennial Allergy, Seasonal Allergies
Asthma Exacerbation Study
- Conditions
- Asthma
- Interventions
- First Posted Date
- 2010-03-15
- Last Posted Date
- 2018-01-24
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 2020
- Registration Number
- NCT01086384
- Locations
- 🇺🇦
GSK Investigational Site, Zaporizhia, Ukraine
Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease
- Conditions
- Patients With Nasal Polyps
- Interventions
- Other: placebo
- First Posted Date
- 2009-11-16
- Last Posted Date
- 2017-09-13
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 7
- Registration Number
- NCT01013701
Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects
- First Posted Date
- 2009-10-23
- Last Posted Date
- 2017-06-22
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 80
- Registration Number
- NCT01000597
- Locations
- 🇦🇺
GSK Investigational Site, Randwick, New South Wales, Australia
A Study of GW685698X in Healthy Japanese Male Subjects
- First Posted Date
- 2009-09-07
- Last Posted Date
- 2017-08-03
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 48
- Registration Number
- NCT00972673
- Locations
- 🇯🇵
GSK Investigational Site, Kagoshima, Japan
Effect of Veramyst on the Nasal and Ocular Symptoms of the Early Reaction to Nasal Challenge With Allergen
- First Posted Date
- 2008-11-17
- Last Posted Date
- 2014-07-08
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 15
- Registration Number
- NCT00791973
- Locations
- 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States
Safety and Efficacy of GW685698X an Inhaled Corticosteroid Once Daily and Twice Daily for the Treatment of Asthma
- First Posted Date
- 2008-10-03
- Last Posted Date
- 2016-12-08
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 190
- Registration Number
- NCT00766090
- Locations
- 🇺🇸
GSK Investigational Site, Waco, Texas, United States
A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Pulmonary Disease, Chronic Obstructive
- First Posted Date
- 2008-08-11
- Last Posted Date
- 2016-12-08
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 60
- Registration Number
- NCT00731822
- Locations
- 🇸🇪
GSK Investigational Site, Stockholm, Sweden
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Non-steroidal Therapy.
- First Posted Date
- 2008-01-29
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 599
- Registration Number
- NCT00603382
- Locations
- 🇸🇪
GSK Investigational Site, Luleå, Sweden
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Low-Dose ICS Therapy.
- First Posted Date
- 2008-01-29
- Last Posted Date
- 2016-12-28
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 622
- Registration Number
- NCT00603278
- Locations
- 🇿🇦
GSK Investigational Site, Mowbray, South Africa
A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Moderate-Dose ICS Therapy.
- First Posted Date
- 2008-01-29
- Last Posted Date
- 2017-09-15
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 627
- Registration Number
- NCT00603746
- Locations
- 🇹🇭
GSK Investigational Site, Bangkok, Thailand
Drug Development Updates
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