MedPath

Cabiralizumab

Generic Name
Cabiralizumab
Drug Type
Biotech
CAS Number
1613144-80-1
Unique Ingredient Identifier
5FJL6W0640
Background

Cabiralizumab is under investigation in clinical trial NCT03502330 (APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma).

Neoadjuvant Nivolumab and Chemotherapy in Patients With Localized Triple-negative Breast Cancer

Phase 1
Active, not recruiting
Conditions
Triple Negative Breast Cancer
Interventions
Procedure: Tumor biopsy
Procedure: Bone marrow
Procedure: Blood draw
First Posted Date
2020-04-02
Last Posted Date
2025-04-23
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
15
Registration Number
NCT04331067
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Washington University School of Medicine, Saint Louis, Missouri, United States

Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

Phase 2
Completed
Conditions
Peripheral T Cell Lymphoma
Interventions
First Posted Date
2019-04-25
Last Posted Date
2024-03-18
Lead Sponsor
University of Michigan Rogel Cancer Center
Target Recruit Count
4
Registration Number
NCT03927105
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Unviersity of Wisconsin, Madison, Wisconsin, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer

Phase 2
Completed
Conditions
Pancreatic Cancer Stage IV
Interventions
First Posted Date
2018-10-05
Last Posted Date
2025-02-06
Lead Sponsor
Hitendra Patel
Target Recruit Count
2
Registration Number
NCT03697564
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UCSD Moores Cancer Center, La Jolla, California, United States

APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma

Phase 1
Completed
Conditions
Non-small Cell Lung Cancer
Advanced Melanoma
Renal Cell Carcinoma
Interventions
First Posted Date
2018-04-18
Last Posted Date
2024-07-03
Lead Sponsor
Yale University
Target Recruit Count
42
Registration Number
NCT03502330
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Yale Cancer Center, New Haven, Connecticut, United States

Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer

Phase 1
Completed
Conditions
Cancer
Interventions
Radiation: Stereotactic Body Radiation Therapy
First Posted Date
2018-02-13
Last Posted Date
2023-02-16
Lead Sponsor
University of Chicago
Target Recruit Count
60
Registration Number
NCT03431948
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Medical Center, Chicago, Illinois, United States

Phase 1 Single and Multiple Dose Study of FPA008 in Healthy Volunteers and Rheumatoid Arthritis Subjects

Phase 1
Terminated
Conditions
Healthy
Rheumatoid Arthritis
Interventions
Drug: Placebo
First Posted Date
2013-10-14
Last Posted Date
2021-12-13
Lead Sponsor
Five Prime Therapeutics, Inc.
Target Recruit Count
66
Registration Number
NCT01962337
Locations
๐Ÿ‡ญ๐Ÿ‡บ

Drug Research Center, Kaposvar, Hungary

๐Ÿ‡ญ๐Ÿ‡บ

PRA Clinical Unit, Budapest, Hungary

๐Ÿ‡ต๐Ÿ‡ฑ

MedPolina, Poznan, Poland

and more 3 locations
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