DeepMed Research

Mosapride

Generic Name: Mosapride

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₅ClFN_₃O_₃

CAS Number: 112885-41-3

Unique Ingredient Identifier: I8MFJ1C0BY

Background: Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.

Indication: 1.功能性消化不良伴有胃灼热、嗳气、恶心、上腹胀等消化道症状；

2.胃食管反流病；

3.糖尿病胃轻瘫；

4.胃大部切除术患者的胃功能障碍。

Clinical Trials

A Comparative Evaluation of Mosapride Versus Metoclopramide for Enteral Feeding Intolerance in Critically Ill Patients

Phase 3

Not yet recruiting

Conditions: Enteral Feeding Intolerance

Interventions: Drug: Mosapride Citrate Tablets
Drug: Metoclopramide 10mg

First Posted Date: 2025-02-14

Last Posted Date: 2025-02-17

Lead Sponsor: Ain Shams University

Target Recruit Count: 100

Registration Number: NCT06826443

Locations: 🇪🇬
Matarya Teaching Hospital, Cairo, Egypt

Zuojin Wan Combined With Rabeprazole or Mosapride for the Treatment of Functional Dyspepsia Combined With Depression

Not Applicable

Not yet recruiting

Conditions: Functional Dyspepsia
Depression

Interventions: Drug: zuojinwan
Drug: Rabeprazole sodium enteric-coated tablets
Drug: mosapride citrate

First Posted Date: 2024-07-01

Last Posted Date: 2024-07-01

Lead Sponsor: Nanjing First Hospital, Nanjing Medical University

Target Recruit Count: 120

Registration Number: NCT06481371

Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation

Not Applicable

Recruiting

Conditions: Constipation

Interventions: Drug: Oral Mosapride Tablets
Device: Deep Acupuncture at Zhongliao Point to Stimulate Sacral Nerve

First Posted Date: 2023-12-05

Last Posted Date: 2023-12-05

Lead Sponsor: Guoliang Wu

Target Recruit Count: 70

Registration Number: NCT06156995

Locations: 🇨🇳
The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China

Efficacy Assessment of Chinese Herbal Medicine Tangweian Recipe Treating Participants With Diabetic Gastroenteropathy

Phase 1

Not yet recruiting

Conditions: Diabetic Gastroenteropathy

Interventions: Drug: Tangweian Recipe
Drug: Mosapride Citrate

First Posted Date: 2023-02-09

Last Posted Date: 2023-02-09

Lead Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Target Recruit Count: 60

Registration Number: NCT05720442

Efficacy of Mosapride on Recovery of Intestinal Motility After Elective Colorectal Cancer Surgery

Not Applicable

Conditions: Colorectal Cancer
Bowel Ileus

Interventions: Drug: Placebo
Drug: Mosapride

First Posted Date: 2021-05-27

Last Posted Date: 2021-09-02

Lead Sponsor: Mahidol University

Target Recruit Count: 44

Registration Number: NCT04905147

Locations: 🇹🇭
Chairat Supsamutchai, Bangkok, Bankok, Thailand

Effect of Mosapride Citrate on Gastrointestinal Motility After Laparoscopic Gastrectomy

Not Applicable

Completed

Conditions: Stomach Cancer

Interventions: Drug: Mosapride citrate
Drug: Placebo

First Posted Date: 2020-07-30

Last Posted Date: 2025-01-08

Lead Sponsor: Gangnam Severance Hospital

Target Recruit Count: 104

Registration Number: NCT04493125

Locations: 🇰🇷
GangnamSeverance Hospital, Seoul, Korea, Republic of

The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia

Not Applicable

Conditions: Gallstone

Interventions: Drug: Motilitone
Drug: Gasmotin

First Posted Date: 2020-04-17

Last Posted Date: 2020-09-30

Lead Sponsor: Yonsei University

Target Recruit Count: 70

Registration Number: NCT04350346

Locations: 🇰🇷
Department of Surgery, Severance hospital, Seoul, Korea, Republic of

Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery

Phase 3

Completed

Conditions: Prevention of Postoperative Ileus

Interventions: Drug: Placebo Oral Tablet
Drug: Mosapride

First Posted Date: 2018-03-26

Last Posted Date: 2018-08-14

Lead Sponsor: Benha University

Target Recruit Count: 400

Registration Number: NCT03477266

Locations: 🇪🇬
Ashraf nassif Elmantwe, Banha, Elqalopia, Egypt

Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia

Phase 3

Completed

Conditions: Functional Dyspepsia

Interventions: Drug: UI05MSP015CT
Drug: Gasmotin

First Posted Date: 2017-07-21

Last Posted Date: 2017-07-21

Lead Sponsor: Korea United Pharm. Inc.

Target Recruit Count: 143

Registration Number: NCT03225248

Efficacy and Safety of DWJ1252 in the Treatment of Functional Dyspepsia (PART 2)

Phase 3

Completed

Conditions: Functional Dyspepsia

Interventions: Drug: DWJ1252
Drug: Gasmotin
Drug: Placebo of Gasmotin
Drug: Placebo of DWJ1252

First Posted Date: 2017-06-12

Last Posted Date: 2019-06-26

Lead Sponsor: Daewoong Pharmaceutical Co. LTD.

Target Recruit Count: 124

Registration Number: NCT03184402

Locations: 🇰🇷
Smg-Snu Boramae Medical Center, Seoul, Korea, Republic of

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