Trimebutine

Generic Name
Trimebutine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C22H29NO5
CAS Number
39133-31-8
Unique Ingredient Identifier
QZ1OJ92E5R
Background

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders . It is ...

Indication

Indicated for symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.

Associated Conditions
Irritable Bowel Syndrome (IBS), Gastrointestinal spasms, Postoperative paralytic ileus
Associated Therapies
-

Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics

First Posted Date
2024-02-21
Last Posted Date
2024-08-16
Lead Sponsor
Universidad de Colima
Target Recruit Count
82
Registration Number
NCT06268964
Locations
🇲🇽

School of Medicine, University of Colima, Colima, Mexico

Impact of Bacillus Clausii Administration on Irritable Bowel Syndrome Patients

First Posted Date
2017-12-02
Last Posted Date
2018-03-13
Lead Sponsor
Hospital Britanico
Target Recruit Count
80
Registration Number
NCT03359499
Locations
🇦🇷

Hospital Britanico, Buenos Aires, Caba, Argentina

Effect of Topical Trimebutine on Pain After Hemorrhoidectomy

Not Applicable
Suspended
Conditions
Interventions
First Posted Date
2017-01-30
Last Posted Date
2017-08-29
Lead Sponsor
Mansoura University
Target Recruit Count
42
Registration Number
NCT03036111
Locations
🇪🇬

Mansoura university hospital, Mansoura, Dakahlia, Egypt

Trimebutine Maleate Combined With Rabeprazole in Patients With Grade A or B Reflux Esophagitis Whose Symptoms Refractory to Rabeprazole

First Posted Date
2016-12-08
Last Posted Date
2023-02-01
Lead Sponsor
Xijing Hospital of Digestive Diseases
Registration Number
NCT02986685
Locations
🇨🇳

Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China

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