Fibrinogen human
- Generic Name
- Fibrinogen human
- Brand Names
- Artiss, Evarrest, Evicel, Fibryga, Riastap, Tachosil, Tisseel, Vistaseal
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 9001-32-5
- Unique Ingredient Identifier
- N94833051K
- Background
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. It is indicated for the treatment ...
- Indication
Human fibrinogen is used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
...
- Associated Conditions
- Bleeding, Dura Mater Nick Cut or Tear, Surgical Bleeding, Acute bleeding episodes
- Associated Therapies
- Tissue Adhesions, Maintenance of surgical hemostasis therapy
Effectiveness of Different Fibrinogen Preparations in Restoring Clot Firmness
- Conditions
- Interventions
- First Posted Date
- 2023-03-22
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- IRCCS Policlinico S. Donato
- Target Recruit Count
- 40
- Registration Number
- NCT05780125
- Locations
- 🇮🇹
IRCCS Policlinico San Donato, San Donato Milanese, MI, Italy
Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-05-26
- Last Posted Date
- 2023-03-28
- Lead Sponsor
- Brno University Hospital
- Target Recruit Count
- 32
- Registration Number
- NCT05391412
- Locations
- 🇨🇿
University Hospital Brno, Brno, Czechia
Administration of Fibrinogen Concentrate for Refractory Bleeding
- Conditions
- Interventions
- First Posted Date
- 2021-10-25
- Last Posted Date
- 2024-10-30
- Target Recruit Count
- 10
- Registration Number
- NCT05091684
- Locations
- 🇫🇷
CHU de Saint-Etienne, Saint-Étienne, France
ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2020-06-16
- Last Posted Date
- 2021-11-03
- Lead Sponsor
- IRCCS Policlinico S. Donato
- Target Recruit Count
- 40
- Registration Number
- NCT04434001
- Locations
- 🇮🇹
IRCCS Policlinico San Donato, San Donato Milanese, MI, Italy
Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients
- First Posted Date
- 2020-05-06
- Last Posted Date
- 2023-10-23
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 30
- Registration Number
- NCT04376762
- Locations
- 🇺🇸
University of Virginia Health System, Charlottesville, Virginia, United States
Use of Fibryga, a Fibrinogen Concentrate in Real World: Retrospective Collection of Clinical Data
- First Posted Date
- 2019-09-27
- Last Posted Date
- 2021-05-13
- Lead Sponsor
- Octapharma
- Target Recruit Count
- 200
- Registration Number
- NCT04106895
- Locations
- 🇫🇷
Le Plessis Robinsin Study Site, Le Plessis-Robinson, France
🇫🇷Nantes Study Site, Nantes, France
🇫🇷Marseille Study Site, Marseille, France
Safety and Efficacy of Fibryga in Congenital Fibrinogen Deficiency
- First Posted Date
- 2019-01-04
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- Octapharma
- Target Recruit Count
- 25
- Registration Number
- NCT03793426
- Locations
- 🇩🇪
Gerinnungszentrum rhein-ruhr, Duisburg, Germany
🇨🇿Fakultní nemocnice Ostrava, Ostrava, Czechia
🇩🇪Gerinnungszentrum Hochtaunus, Hamburg, Germany
Patient Blood Management for Massive Obstetric Hemorrhage
- Conditions
- Interventions
- First Posted Date
- 2018-12-24
- Last Posted Date
- 2021-06-08
- Lead Sponsor
- Angel Augusto Perez Calatayud
- Target Recruit Count
- 100
- Registration Number
- NCT03784794
- Locations
- 🇲🇽
Hospital de Especialidades Del Niño Y La Mujer, Querétaro City, Queretaro, Mexico
The Effects of Fibrinogen Concentrate Infusion on Blood Loss and Allogeneic Blood Conservation in Scoliosis Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-06-12
- Last Posted Date
- 2020-03-02
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 102
- Registration Number
- NCT03183479
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China
Human Fibrinogen Concentrate in Pediatric Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2016-07-04
- Last Posted Date
- 2021-09-16
- Target Recruit Count
- 30
- Registration Number
- NCT02822599
- Locations
- 🇺🇸
Nickalus Children's Hospital f/k/a Miami Children's Hospital, Miami, Florida, United States
🇺🇸Nicklaus Children's Hospital, Miami, Florida, United States
Drug Development Updates
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