MedPath

Teropavimab

Generic Name
Teropavimab

Albuvirtide and 3BNC117 as Long-Acting Maintenance Therapy in Virologically Suppressed Subjects

Phase 2
Conditions
HIV-1-infection
Interventions
First Posted Date
2018-10-25
Last Posted Date
2021-09-29
Lead Sponsor
Frontier Biotechnologies Inc.
Target Recruit Count
80
Registration Number
NCT03719664
Locations
🇺🇸

ABT-3BNC117_201 Investigational Site, New York, New York, United States

First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS

Phase 1
Completed
Conditions
Human Immunodeficiency Virus
Interventions
First Posted Date
2018-06-13
Last Posted Date
2021-08-04
Lead Sponsor
Rockefeller University
Target Recruit Count
77
Registration Number
NCT03554408
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

3BNC117 and 10-1074 in ART-treated Individuals

Phase 1
Completed
Conditions
Human Immunodeficiency Virus
Interventions
Other: Analytical treatment interruption
First Posted Date
2018-05-16
Last Posted Date
2022-02-15
Lead Sponsor
Rockefeller University
Target Recruit Count
26
Registration Number
NCT03526848
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

🇺🇸

Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, United States

3BNC117-LS First-in-Human Phase 1 Study

Phase 1
Completed
Conditions
Human Immunodeficiency Virus
Interventions
Drug: Placebo
First Posted Date
2017-08-18
Last Posted Date
2021-02-03
Lead Sponsor
Rockefeller University
Target Recruit Count
43
Registration Number
NCT03254277
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ART

Phase 2
Completed
Conditions
Hiv
Interventions
Drug: Antiretrovirals
First Posted Date
2017-02-02
Last Posted Date
2025-04-18
Lead Sponsor
Aarhus University Hospital
Target Recruit Count
60
Registration Number
NCT03041012
Locations
🇬🇧

Guy's and St Thomas', London, United Kingdom

🇩🇰

Department of Infectious Diseases, Odense, Denmark

🇩🇰

Dept. of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark

and more 1 locations

Romidepsin Plus 3BNC117 Phase 2a Study

Phase 2
Completed
Conditions
Human Immunodeficiency Virus (HIV)
Interventions
First Posted Date
2016-07-29
Last Posted Date
2022-07-14
Lead Sponsor
Rockefeller University
Target Recruit Count
48
Registration Number
NCT02850016
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

🇩🇰

Aarhus University Hospital, Aarhus, Denmark

🇩🇪

University of Cologne, Cologne, Germany

3BNC117 and 10-1074 in HIV-infected Individuals

Phase 1
Completed
Conditions
Human Immunodeficiency Virus (HIV)
Interventions
Drug: Placebo
Other: Analytical treatment interruption
First Posted Date
2016-07-07
Last Posted Date
2018-08-21
Lead Sponsor
Rockefeller University
Target Recruit Count
34
Registration Number
NCT02825797
Locations
🇩🇪

University Hospital of Cologne, Cologne, Germany

🇺🇸

The Rockefeller University, New York, New York, United States

3BNC117 and 10-1074 in HIV Uninfected Adults

Phase 1
Completed
Conditions
Human Immunodeficiency Virus
Interventions
First Posted Date
2016-07-06
Last Posted Date
2018-04-17
Lead Sponsor
Rockefeller University
Target Recruit Count
24
Registration Number
NCT02824536
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

A Study of the Safety and Antiretroviral Activity of 3BNC117

Phase 2
Completed
Conditions
HIV-1 Infection
Interventions
Other: Antiretroviral Treatment Interruption
First Posted Date
2015-10-28
Last Posted Date
2021-06-16
Lead Sponsor
Rockefeller University
Target Recruit Count
17
Registration Number
NCT02588586
Locations
🇺🇸

Weill Cornel Medical Center, New York, New York, United States

🇺🇸

The Rockefeller University, New York, New York, United States

3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption

Phase 2
Completed
Conditions
HIV-1 Infection
Interventions
Other: ART Interruption
First Posted Date
2015-05-18
Last Posted Date
2020-07-23
Lead Sponsor
Rockefeller University
Target Recruit Count
16
Registration Number
NCT02446847
Locations
🇺🇸

The Rockefeller University, New York, New York, United States

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