MedPath

AZD-5718

Generic Name
AZD-5718

Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-Severe Uncontrolled Asthma

Phase 2
Recruiting
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2022-02-22
Last Posted Date
2025-05-08
Lead Sponsor
AstraZeneca
Target Recruit Count
666
Registration Number
NCT05251259
Locations
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Research Site, Watford, United Kingdom

Study to Assess Relative Bioavailability and Safety of AZD5718 in Healthy Volunteers

Phase 1
Completed
Conditions
Chronic Kidney Disease
Interventions
First Posted Date
2021-02-02
Last Posted Date
2021-12-06
Lead Sponsor
AstraZeneca
Target Recruit Count
16
Registration Number
NCT04734275
Locations
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Research Site, London, United Kingdom

PASSIvation of Vulnerable Plaque With AZD5718 in AcuTe Coronary syndromE

Phase 2
Terminated
Conditions
Acute Coronary Syndrome
Interventions
Drug: Placebo
First Posted Date
2020-10-23
Last Posted Date
2025-04-27
Lead Sponsor
National University Heart Centre, Singapore
Target Recruit Count
243
Registration Number
NCT04601467
Locations
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Ng Teng Fong General Hospital (NTFGH), Singapore, Singapore

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Tan Tock Seng Hospital (TTSH), Singapore, Singapore

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North Shore Hospital, Auckland, New Zealand

and more 5 locations

A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

Phase 2
Terminated
Conditions
Chronic Kidney Disease
Interventions
First Posted Date
2020-07-30
Last Posted Date
2024-12-20
Lead Sponsor
AstraZeneca
Target Recruit Count
613
Registration Number
NCT04492722
Locations
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Research Site, Zhytomyr, Ukraine

A Study to Assess the Effect of Multiple Doses of AZD5718 on Pharmacokinetics of Oral Midazolam in Healthy Subjects

Phase 1
Completed
Conditions
Cardiovascular Disease
Interventions
First Posted Date
2020-07-30
Last Posted Date
2020-11-03
Lead Sponsor
AstraZeneca
Target Recruit Count
14
Registration Number
NCT04492709
Locations
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Research Site, Harrow, United Kingdom

AZD5718 Phase IIa Study to Evaluate Efficacy, Safety and Tolerability of Oral AZD5718 in Patients With Coronary Artery Disease (CAD).

Phase 2
Completed
Conditions
Coronary Artery Disease
Interventions
Drug: Placebo
First Posted Date
2017-10-23
Last Posted Date
2021-06-30
Lead Sponsor
AstraZeneca
Target Recruit Count
129
Registration Number
NCT03317002
Locations
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Research Site, Uppsala, Sweden

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