Nitric Oxide
- Generic Name
- Nitric Oxide
- Brand Names
- Inomax, Kinox, Noxivent, INOmax
- Drug Type
- Small Molecule
- Chemical Formula
- NO
- CAS Number
- 10102-43-9
- Unique Ingredient Identifier
- 31C4KY9ESH
- Background
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants.
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- Indication
For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
- Associated Conditions
- Hypoxic Respiratory Failure
- Associated Therapies
- -
Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary Bypass
- Conditions
- Interventions
- First Posted Date
- 2018-04-18
- Last Posted Date
- 2019-07-05
- Target Recruit Count
- 60
- Registration Number
- NCT03500783
Nitric Oxide Administration During Pediatric Cardiopulmonary Bypass Surgery to Prevent Platelet Activation
- Conditions
- Interventions
- First Posted Date
- 2018-03-06
- Last Posted Date
- 2020-08-13
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 40
- Registration Number
- NCT03455218
- Locations
- 🇺🇸
Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States
Inhaled Nitric Oxide for Patients With MABSC
- First Posted Date
- 2017-07-06
- Last Posted Date
- 2019-07-09
- Lead Sponsor
- Beyond Air Inc.
- Target Recruit Count
- 9
- Registration Number
- NCT03208764
- Locations
- 🇮🇱
Rambam Medical Center, Haifa, Israel
Registry to Evaluate INOmax in Newborn Babies With Pulmonary Hypertension
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2020-06-18
- Lead Sponsor
- Mallinckrodt
- Target Recruit Count
- 140
- Registration Number
- NCT03132428
- Locations
- 🇺🇸
Loma Linda University Health Care, Loma Linda, California, United States
🇺🇸University of Chicago Comer Children's Hospital, Chicago, Illinois, United States
🇺🇸University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Inhaled Nitric Oxide After Out-of-Hospital Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2017-03-14
- Last Posted Date
- 2022-04-25
- Lead Sponsor
- Cameron Dezfulian
- Target Recruit Count
- 57
- Registration Number
- NCT03079102
- Locations
- 🇺🇸
UPMC McKeesport, McKeesport, Pennsylvania, United States
🇺🇸UPMC Presbyterian Hospital, Pittsburgh, Pennsylvania, United States
🇺🇸UPMC Mercy Hospital, Pittsburgh, Pennsylvania, United States
Evaluation of the Efficacy Safety and Tolerability of Nitric Oxide Given Intermittently Via Inhalation to Subjects With Bronchiolitis
- First Posted Date
- 2017-02-15
- Last Posted Date
- 2019-07-09
- Lead Sponsor
- Beyond Air Inc.
- Target Recruit Count
- 69
- Registration Number
- NCT03053388
- Locations
- 🇮🇱
Sheba Medical Center, Ramat Gan, Israel
🇮🇱Barzili Medical Center, Ashkelon, Israel
🇮🇱Carmel Medical Center, Haifa, Israel
Diffuse Optical Monitoring with Inhaled Nitric Oxide
- First Posted Date
- 2017-01-18
- Last Posted Date
- 2024-11-26
- Lead Sponsor
- Steven Messe
- Target Recruit Count
- 40
- Registration Number
- NCT03023449
- Locations
- 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Nitric Oxide Releasing Solution (NORS) Footbath to Treat Athlete's Foot
- First Posted Date
- 2016-08-18
- Last Posted Date
- 2019-09-20
- Lead Sponsor
- Nitric Solutions Inc.
- Target Recruit Count
- 20
- Registration Number
- NCT02871011
- Locations
- 🇨🇦
Fairmont Medical Clinic, Vancouver, British Columbia, Canada
Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.
- Conditions
- Interventions
- First Posted Date
- 2016-07-19
- Last Posted Date
- 2022-11-10
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 250
- Registration Number
- NCT02836899
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH
- First Posted Date
- 2016-04-12
- Last Posted Date
- 2018-09-24
- Lead Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
- Target Recruit Count
- 10
- Registration Number
- NCT02734953
- Locations
- 🇺🇸
Allegheny General Hospital, Pittsburgh, Pennsylvania, United States
Drug Development Updates
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