MedPath

Brequinar

Generic Name
Brequinar
Drug Type
Small Molecule
Chemical Formula
C23H15F2NO2
CAS Number
96187-53-0
Unique Ingredient Identifier
5XL19F49H6

Brequinar Combined With Dipyridamole in Patients With Mild to Moderate COVID-19

Phase 2
Terminated
Conditions
COVID-19
Interventions
First Posted Date
2021-12-22
Last Posted Date
2023-11-07
Lead Sponsor
Clear Creek Bio, Inc.
Target Recruit Count
26
Registration Number
NCT05166876
Locations
๐Ÿ‡ฎ๐Ÿ‡ณ

RIMS - Government Medical College, Srikakulam, Andhra Pradesh, India

๐Ÿ‡ฎ๐Ÿ‡ณ

King George Hospital, Visakhapatnam, Andhra Pradesh, India

๐Ÿ‡ฎ๐Ÿ‡ณ

JIPMER Hospital, Pondicherry, Puducherry, India

and more 4 locations

CRISIS2: A Phase 2 Study of the Safety and Antiviral Activity of Brequinar in Non-hospitalized Pts With COVID-19

Phase 2
Completed
Conditions
COVID-19 Infection
Interventions
Drug: Placebo
First Posted Date
2020-10-05
Last Posted Date
2022-04-19
Lead Sponsor
Clear Creek Bio, Inc.
Target Recruit Count
115
Registration Number
NCT04575038
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Synexus Clinical Research US, Inc. - Olympus Family Medicine, Salt Lake City, Utah, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ark Clinical Research, Long Beach, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Central Alabama Research, Homewood, Alabama, United States

and more 11 locations

Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19

Phase 1
Completed
Conditions
COVID-19
Interventions
Other: Standard of Care
First Posted Date
2020-06-11
Last Posted Date
2022-02-17
Lead Sponsor
Clear Creek Bio, Inc.
Target Recruit Count
25
Registration Number
NCT04425252
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of South Florida/Tampa General, Tampa, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Hartford Hospital, Hartford, Connecticut, United States

๐Ÿ‡บ๐Ÿ‡ธ

Temple University, Philadelphia, Pennsylvania, United States

and more 2 locations
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