Loteprednol etabonate
- Generic Name
- Loteprednol etabonate
- Brand Names
- Eysuvis, Inveltys, Lotemax
- Drug Type
- Small Molecule
- Chemical Formula
- C24H31ClO7
- CAS Number
- 82034-46-6
- Unique Ingredient Identifier
- YEH1EZ96K6
- Background
Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal...
- Indication
A number of prescription loteprednol etabonate ophthalmic products are specifically indicated for the treatment of post-operative inflammation and pain following ocular surgery .
- Associated Conditions
- Dry Eye Syndrome (DES), Eye Pain, Ocular Inflammation
- Associated Therapies
- -
Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax
- Conditions
- Interventions
- First Posted Date
- 2020-09-21
- Last Posted Date
- 2023-10-11
- Lead Sponsor
- Thomas Chester, OD
- Target Recruit Count
- 30
- Registration Number
- NCT04555694
- Locations
- 🇺🇸
Cleveland Eye Clinic, Brecksville, Ohio, United States
Evaluation of the Safety, Systemic Pharmacokinetics, and Tolerability of Single and Repeat Ocular Installations
- First Posted Date
- 2017-04-04
- Last Posted Date
- 2017-05-18
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 15
- Registration Number
- NCT03098953
- Locations
- 🇺🇸
Valeant Site 01, Inglewood, California, United States
A Phase IV, Randomized, Parallel Group, Investigator-Masked Evaluation of the Effect of Loteprednol Etabonate Ophthalmic Gel 0.5% on the Initiation of Dry Eye Treatment With Restasis®
- Conditions
- Interventions
- First Posted Date
- 2014-01-07
- Last Posted Date
- 2015-03-18
- Lead Sponsor
- Edward Holland, MD
- Registration Number
- NCT02028312
- Locations
- 🇺🇸
Cincinnati Eye Institute, Edgewood, Kentucky, United States
Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty
- Conditions
- Interventions
- First Posted Date
- 2013-05-15
- Last Posted Date
- 2015-05-15
- Lead Sponsor
- Cornea Research Foundation of America
- Target Recruit Count
- 167
- Registration Number
- NCT01853696
- Locations
- 🇺🇸
Price Vision Group, Indianapolis, Indiana, United States
Comparison the Effects of Dexamethasone and Loteprednol on Epithelial Healing
- Conditions
- Interventions
- First Posted Date
- 2012-11-12
- Last Posted Date
- 2014-03-17
- Lead Sponsor
- Khon Kaen University
- Target Recruit Count
- 32
- Registration Number
- NCT01724892
- Locations
- 🇹🇭
Onsiri Thanathanee, Khon Kaen, Thailand
🇹🇭Srinagarind Hospital, Khon Kaen, Thailand
Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.
- Conditions
- Interventions
- First Posted Date
- 2011-11-21
- Last Posted Date
- 2019-06-11
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 107
- Registration Number
- NCT01475643
- Locations
- 🇺🇸
Bausch & Lomb Inc, Rochester, New York, United States
Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
- Conditions
- Interventions
- First Posted Date
- 2011-09-29
- Last Posted Date
- 2019-08-06
- Target Recruit Count
- 23
- Registration Number
- NCT01443442
- Locations
- 🇺🇸
Eye Car Center, Southern California college of Optometry, Fullerton, California, United States
🇺🇸Eye Care Center, Southern Caalifornia College of Optometry, Fullerton, California, United States
A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%
- Conditions
- Interventions
- First Posted Date
- 2011-09-21
- Last Posted Date
- 2019-11-19
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 140
- Registration Number
- NCT01437982
- Locations
- 🇰🇷
Bausch & Lomb Korea Ltd, Seoul, Korea, Republic of
Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
- Conditions
- Interventions
- First Posted Date
- 2010-02-02
- Last Posted Date
- 2012-01-13
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 407
- Registration Number
- NCT01060072
- Locations
- 🇺🇸
Bausch & Lomb, Rochester, New York, United States
Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
- Conditions
- Interventions
- First Posted Date
- 2009-11-10
- Last Posted Date
- 2012-01-09
- Lead Sponsor
- Bausch & Lomb Incorporated
- Target Recruit Count
- 406
- Registration Number
- NCT01010633
- Locations
- 🇺🇸
Bausch & Lomb, Inc., Rochester, New York, United States
Drug Development Updates
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