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Propylthiouracil

Generic Name
Propylthiouracil
Drug Type
Small Molecule
Chemical Formula
C7H10N2OS
CAS Number
51-52-5
Unique Ingredient Identifier
721M9407IY

Overview

A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)

Background

A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)

Indication

Used to manage hyperthyroidism which is due to an overactive thyroid gland (Grave's disease).

Associated Conditions

  • Hyperthyroidism
  • Thyrotoxic crisis

FDA Approved Products

Propylthiouracil
Manufacturer:Macleods Pharmaceuticals Limited
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/05/18
NDC:33342-314
PROPYLTHIOURACIL
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/08/15
NDC:72162-2072
Propylthiouracil
Manufacturer:Actavis Pharma, Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2021/10/31
NDC:0228-2348
PROPYLTHIOURACIL
Manufacturer:QUAGEN PHARMACEUTICALS LLC
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/02/15
NDC:70752-171
Propylthiouracil
Manufacturer:American Health Packaging
Route:ORAL
Strength:50 mg in 1 1
Approved: 2022/10/04
NDC:68084-964

Singapore Approved Products

PROPYL TABLET 50 mg
Manufacturer:SRIPRASIT PHARMA CO LTD
Form:TABLET
Strength:50 mg
Online:Yes
Approved: 2001/10/08
Approval:SIN11695P
PROPYLTHIOURACIL TABLETS BP 50 mg
Manufacturer:PT ACTAVIS INDONESIA
Form:TABLET
Strength:50 mg
Online:Yes
Approved: 1988/05/04
Approval:SIN00772P
PROPYLTHIOURACIL TABLET BP 50 mg
Manufacturer:RECIPHARM LIMITED
Form:TABLET
Strength:50 mg
Online:Yes
Approved: 1990/06/14
Approval:SIN04664P

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