Pimonidazole
- Generic Name
- Pimonidazole
- Drug Type
- Small Molecule
- Chemical Formula
- C11H18N4O3
- CAS Number
- 70132-50-2
- Unique Ingredient Identifier
- 46JO4D76R2
- Background
Pimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.
Evaluation of Hypoxia in Primary Melanoma
- First Posted Date
- 2025-02-17
- Last Posted Date
- 2025-05-08
- Lead Sponsor
- Yana Najjar
- Target Recruit Count
- 50
- Registration Number
- NCT06831071
- Locations
- 🇺🇸
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
Hypoxia Driven Metabolic Response in Oesophagogastric Adenocarcinoma
- Conditions
- OESOPHAGO-GASTRIC CARCINOMA
- Interventions
- First Posted Date
- 2024-11-01
- Last Posted Date
- 2025-03-07
- Lead Sponsor
- Imperial College London
- Target Recruit Count
- 120
- Registration Number
- NCT06669663
- Locations
- 🇬🇧
Imperial College NHS Healthcare Trust, London, United Kingdom
Hypoxia-driven Prostate Cancer Genomics (HYPROGEN)
- Conditions
- Prostate CancerHypoxia
- Interventions
- Procedure: Radical ProstatectomyDiagnostic Test: CT-guided Bone BiopsyDiagnostic Test: TRUS-guided Targeted Transperineal Prostate BiopsyDiagnostic Test: Prostate MRI scansDiagnostic Test: Whole-body MRIOther: Baseline bloods - for germline testingOther: Baseline bloods for CTCs and ct DNA taken at same time as baseline bloods in Arm 1Other: Post-pimonidazole bloods for CTCs and ctDNA
- First Posted Date
- 2023-01-27
- Last Posted Date
- 2023-01-27
- Lead Sponsor
- The Christie NHS Foundation Trust
- Target Recruit Count
- 60
- Registration Number
- NCT05702619
- Locations
- 🇬🇧
The Christie NHS Foundation Trust, Manchester, United Kingdom
Evolution of Metabolic and Immune Dysfunction in In-transit Melanoma
- First Posted Date
- 2020-12-08
- Last Posted Date
- 2025-05-08
- Lead Sponsor
- Yana Najjar
- Target Recruit Count
- 20
- Registration Number
- NCT04658303
- Locations
- 🇺🇸
UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
Total Tumor Mapping (TTM) for Resectable Pancreatic Cancer
- Conditions
- Resectable Pancreatic CancerPancreatic Cancer
- Interventions
- Procedure: Surgical Resection
- Locations
- 🇺🇸
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States
FAZA PET/MRI Sarcoma
- First Posted Date
- 2018-02-01
- Last Posted Date
- 2025-02-10
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 50
- Registration Number
- NCT03418818
- Locations
- 🇨🇦
University Health Network, Toronto, Ontario, Canada
Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride
- First Posted Date
- 2018-01-25
- Last Posted Date
- 2025-04-02
- Lead Sponsor
- Thomas Gleason
- Target Recruit Count
- 40
- Registration Number
- NCT03410420
- Locations
- 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer
- Conditions
- Tongue Cancer
- Interventions
- Radiation: (18)F-Fluoroazomycin arabinoside
- First Posted Date
- 2017-06-08
- Last Posted Date
- 2024-08-12
- Lead Sponsor
- Sunnybrook Health Sciences Centre
- Target Recruit Count
- 10
- Registration Number
- NCT03181035
- Locations
- 🇨🇦
Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Hypoxia Analysis in Head and/or Neck Cancer
- First Posted Date
- 2015-04-10
- Last Posted Date
- 2016-06-17
- Lead Sponsor
- Marius Gustav Bredell
- Target Recruit Count
- 10
- Registration Number
- NCT02414048
- Locations
- 🇨🇭
Department of Cranio-, Maxillofacial and Oral Surgery, Zürich, Switzerland
Prostate Hypoxia - TIC
- First Posted Date
- 2014-03-24
- Last Posted Date
- 2024-06-18
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 39
- Registration Number
- NCT02095249
- Locations
- 🇨🇦
University Health Network, Toronto, Ontario, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.