MedPath

Hydroxyurea

Generic Name
Hydroxyurea
Brand Names
Droxia, Hydrea, Siklos, Xromi
Drug Type
Small Molecule
Chemical Formula
CH4N2O2
CAS Number
127-07-1
Unique Ingredient Identifier
X6Q56QN5QC

Overview

An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.

Background

An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.

Indication

Hydroxyurea is indicated to reduce the frequency of painful crises and to reduce the need for blood transfusions in adult and pediatric patients, 2 years of age and older, with sickle cell anemia with recurrent moderate to severe painful crises.

Associated Conditions

  • Chronic Myelogenous Leukemia (CML)
  • Essential Thrombocythemia (ET)
  • Head and Neck Primary Squamous Cell Carcinoma
  • Hypereosinophilic Syndrome (HES)
  • Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN)
  • Meningiomas
  • Polycythemia Vera (PV)
  • Sickle Cell Crisis
  • Vaso-occlusive Crisis

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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