Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease
- First Posted Date
- 2024-08-29
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- Theravia
- Target Recruit Count
- 50
- Registration Number
- NCT06578507
- Locations
- 🇬🇫
Centre hospitalier de Cayenne, Cayenne, French Guiana
🇫🇷Centre Hospitalier Intercommunal Créteil, Créteil, France
🇫🇷Hôpital Bicêtre, Le Kremlin-Bicêtre, France
Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease.
- First Posted Date
- 2022-07-22
- Last Posted Date
- 2022-11-23
- Lead Sponsor
- Theravia
- Target Recruit Count
- 33
- Registration Number
- NCT05470270
- Locations
- 🇫🇷
InterCommunal Hospital Centre of Creteil, Créteil, France
🇫🇷Necker University Hospital, Paris, France
🇫🇷Robert Debré Hospital, Paris, France
A Bioequivalence Study to Compare the Pharmacokinetics of Two Formulations of Siklos® in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2021-08-27
- Last Posted Date
- 2021-10-07
- Lead Sponsor
- Theravia
- Target Recruit Count
- 28
- Registration Number
- NCT05025072
- Locations
- 🇬🇧
Simbec-Orion Clinical Pharmacology, Merthyr Tydfil, United Kingdom
ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study
- First Posted Date
- 2021-01-13
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Theravia
- Target Recruit Count
- 2093
- Registration Number
- NCT04707235
- Locations
- 🇫🇷
Bordeaux Hospital Adults, Bordeaux, France
🇫🇷Bordeaux Hospital Children, Bordeaux, France
🇫🇷Tours Regional University Hospital Center Adults, Chambray-lès-Tours, France
SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial)
- Conditions
- Interventions
- First Posted Date
- 2019-01-16
- Last Posted Date
- 2024-08-27
- Lead Sponsor
- Theravia
- Target Recruit Count
- 99
- Registration Number
- NCT03806452
- Locations
- 🇲🇱
Centre de Recherche et de Lutte contre la Drépanocytose de Bamako (CRLD), Bamako, Mali
🇬🇵CHU Pointe-à -Pitre/Abymes, Pointe-à -Pitre, Guadeloupe
🇫🇷CHU d'Angers, Angers, France
Plasma DNA and Vascular Remodelling in Patients With Sickle Cell Disease
- Conditions
- Interventions
- First Posted Date
- 2016-03-29
- Last Posted Date
- 2020-01-09
- Lead Sponsor
- Theravia
- Target Recruit Count
- 44
- Registration Number
- NCT02721472
- Locations
- 🇫🇷
Hôpital Avicenne, Bobigny, Ile De France, France
Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2021-10-12
- Lead Sponsor
- Theravia
- Target Recruit Count
- 40
- Registration Number
- NCT02522104
- Locations
- 🇫🇷
Centre de Référence des Syndromes Drépanocytaires Majeurs, Hôpital Henri-Mondor, Creteil, France
European Sickle Cell Disease Cohort - Hydroxyurea
- Conditions
- First Posted Date
- 2015-08-06
- Last Posted Date
- 2020-03-19
- Lead Sponsor
- Theravia
- Target Recruit Count
- 1906
- Registration Number
- NCT02516579
- Locations
- 🇫🇷
Hôpital Necker enfants, maladies infectieuses et tropicales, Paris, France
🇫🇷Centre Hospitalier de Gonesse, médecine interne, Gonesse, France
🇫🇷CHU Timone, Marseille, France