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FX06

Generic Name
FX06
Drug Type
Biotech
Background

FX06 is a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bbeta(15-42)). It prevents leukocyte migration through the gap junctions of endothelial cells. FX06 has proven safe in acute and subchronic toxicological studies and recently entered clinical development. It is being developed by Fibrex Medical Inc.

Indication

Investigated for use/treatment in cardiac reperfusion injury and myocardial infarction.

FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia

Phase 2
Completed
Conditions
Ards
Covid19
Pneumonia
Interventions
Drug: Placebo of FX06
First Posted Date
2020-11-05
Last Posted Date
2021-06-22
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
50
Registration Number
NCT04618042
Locations
🇫🇷

Service de Médecine Intensive Réanimation - CHI de Poissy, Chambourcy, France

🇫🇷

Service de Médecine Intensive Réanimation - CHU Angers, Angers, France

🇫🇷

Hôpital Pitié Salpêtrière, Paris, France

Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury

Phase 2
Completed
Conditions
Myocardial Ischemia
Coronary Disease
Myocardial Infarction
Interventions
Procedure: Percutaneous coronary intervention
First Posted Date
2006-05-17
Last Posted Date
2007-12-04
Lead Sponsor
Fibrex Medical Research & Development GmbH
Target Recruit Count
234
Registration Number
NCT00326976
Locations
🇦🇹

Wilhelminen-Spital, Vienna, Austria

🇧🇪

Academisch Ziekenhuis van de vrije Universiteit, Brussels, Belgium

🇩🇪

Universitätsklinikum Aachen, Aachen, Germany

and more 29 locations
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