FX06 is a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bbeta(15-42)). It prevents leukocyte migration through the gap junctions of endothelial cells. FX06 has proven safe in acute and subchronic toxicological studies and recently entered clinical development. It is being developed by Fibrex Medical Inc.
Investigated for use/treatment in cardiac reperfusion injury and myocardial infarction.
Service de Médecine Intensive Réanimation - CHI de Poissy, Chambourcy, France
Service de Médecine Intensive Réanimation - CHU Angers, Angers, France
Hôpital Pitié Salpêtrière, Paris, France
Wilhelminen-Spital, Vienna, Austria
Academisch Ziekenhuis van de vrije Universiteit, Brussels, Belgium
Universitätsklinikum Aachen, Aachen, Germany
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